Clinical presentation of RA

Question 1

What are symptoms ?

Answer 1

-fatigue
-weakness
-anorexia
- diffuse MS pain
= nonspecific symp

• pain involved jts
  prolonged morning joint stifness

Question 2

what are signs

Answer 2

• MCP, PIP, MTP - wrist joints
• joint mov symmetric
• limited joint function
• swan neck / boutonneire deformities
• joitn inflamm - tenderness, warmth, swelling , erythema
• low grade fever

Question 3

what extraarticular signs?

Answer 3

1. skin - sc nodules
2. ocular - keratoconjunctivtiies sicca, scleritis
3. pulmonary - intersitial fibrosis, pulmonary nodules, pleuritis, pleural effusions
4. vasculitis - ischaemic ulcers, skin lesions, leukocytoclastic vaculitis
5. neutrological - peripheral neuropathy , felty syndrome
6. haematologyic - anemic , thrombocytosis

Question 4

what are lab tests done for RA?

Answer 4

1. • RF
2. elvated ESR , CRP
3. FBC - increase WBC, anemia, thrombocytosis
4. • ACPA

Question 5

diagnostic tests

Answer 5

1. synovial fluid analysis
2. joint x- rays - evulate damage
3. MRI - detect erosions

Question 6

Assess disease acitivty

Answer 6

• clinical disease act indec - CDAI
• simplified disease act index - SDAI
  DAS-28 NUMBER SWOLLLEN AND TENDER JOINTS , ESR/ CRP subective measure of patients health