Clinical Neuroanatomy Flashcards

1
Q

Hyperacute presentation

  • time frame
  • possible atieology
A

Hyperacute presentation

  • instantenous, seconds
  • possible vascular pathology
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2
Q

Acute presentation

  • time frame
  • possible atieology
A

Acute

  • minutes to days
  • possible inflammatory, infectious pathology
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3
Q

Subacute presentation

  • time frame
  • possible atieology
A

Subacute

  • weeks to months
  • possible etiology: neoplasia
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4
Q

Chronic presentation

  • time frame
  • possible atieology
A

Chronic presentation

  • years
  • possible aetiology: genetic, degenerative
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5
Q

hemiparesis vs hemiplegia

A

Hemiparesis - weakness on one side of the body

Hemiplegia - paralysis of one side of the body

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6
Q

Aphasia vs dysphasia

A

Aphasialoss of the ability to effectively communicate verbally due to a cognitive communication deficit. May be expressive, receptive or both

Dysphasia – cognitive communication impairment that does not prohibit verbal communication. May be expressive or receptive.

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7
Q

What’s anarthria and what’s dysarthria?

A

Anarthria/dysarthria – loss of/difficulty with verbal communication due to problems articulating words, for example, due to bulbar palsy or cerebellar disease

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8
Q

What’s apraxia; what’s dyspraxia?

What are the types?

A

Apraxia/dyspraxia – loss of/difficulty planning to reach a given motor endpoint or perform sequenced activity.

May be (types):

  • ideational -> unable to sequence an imagined act e.g. ‘turn a key’
  • ideomotor -> unable to mimic an observed posture or movement
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9
Q

What pyramidal tract connects?

A

Pyramidal corticospinal -> from motor cortex to lower motor neurons (via pyramid shaped tracts in brainstem)

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10
Q

Extrapyramidal tract

  • where does it go from?
  • what does it do?
A

Extrapyramidal tract

  • goes from basal ganglia

Primes motor cortex to produce activity and suppress the ones the areas that are not needed

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11
Q

What does the cerebellum do in terms of movement?

A

Cerebellar area -> fine-tuning of activity; comparing planned with actual movements -> learned movements can be acted upon (performed)

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12
Q

What does reticular formation do?

A

It is crucial for arousal and autonomic activity

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13
Q

What gives rise to cranial nerves? Where anatomically is it located?

A

Cranial nuclei - locate in the brain stream

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14
Q

Where do cranial nerves 1-2 arise from?

A

From the brain

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15
Q

Where do cranial nerves 3-4 arise from?

A

Midbrain

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16
Q

Where do cranial nerves 5-8 arise from?

A

Pons

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17
Q

Where do cranial nerves 9-12 arise from?

A

Medulla

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18
Q

What’s the role of Medial Longitudinal Fasciculus (MLF)?

A

Medial Longitudinal Fasciculus

It’s the main pathway that connects the vestibular and cochlear nuclei -> control the ‘gaze’ (oculomotor, trochlear and abducens)

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19
Q

Where does the spinal cord terminate?

A

T12 or L1 level with the conus _> which gives rise to cauda equina (lumbar spine houses cauda equina)

*cauda equina from T12 / L1 to the coccyx

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20
Q

Where is C8 nerve root located?

A

Between C7 and T1 vertebrae

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21
Q

Label the picture

A
22
Q

What’s input to the brain?

What’s the output?

A
  • Input - 5 senses, propriception
  • Output - motor and speech & autonomic regulation
23
Q

What brain lobes do optic radiations go through?

A

Parietal and temporal

24
Q

Where in the optic pathway do the projections from L and R visual fields go to?

A

Lateral Geniculate Nucleus

25
Q

What are the parts of ‘association cortex’?

A

Association cortex:

  • prefrontal -> executive function
  • posterior -> sensory
26
Q

What are main (2) subcortical parts of the brain?

A
  • thalamus
  • basal ganglia
27
Q

What is the function of (in terms of movement):

  • basal ganglia
  • cerebellum
A

Basal ganglia -> Initiation and amplification of movement

Cerebellum -> fine tuning

28
Q

L and R Brain hemispheres and (3) areas/skills that they are responsible for

A

L -> language, praxis (learnt motor movement), maths

R -> music, space, attention

29
Q

Midbrain

  • cranial nerves in it
  • what centres are located there
A

Midbrain

  • CN III and IV
  • auditory and visual reflex centres
30
Q

Pons

  • what cranial nerves are there
  • what does it do?
A

Pons

  • CN V - VIII
  • relay between cerebellum and cerebrum
31
Q

Medulla

  • what cranial nerves are there
  • what centres does it contain?
A

Medulla

  • CN IX - XII
  • centres: cardiac, respiratory, vasomotor and autonomic
32
Q

Front dermatomes (draw)

A
33
Q

Back dermatomes (draw)

A
34
Q

What is spondylosis?

*complications

A

Spondylosis

*If severe, it may cause pressure on the spinal cord or nerve roots with subsequent sensory or motor disturbances, such as pain, paresthesia, imbalance, and muscle weakness in the limbs.

35
Q

What nerve supplies:

Wrist and finger extensors

A

Radial nerve

36
Q

What nerve supplies

LOAF (lateral two lumbricals. opponens pollicis.abductor pollicis brevis.flexor pollicis brevis) muscles, grip, sensory lateral hand

A

Median nerve

37
Q

What nerve supplies small muscles of hand and grip?

A

Ulnar n.

38
Q

Diffuse vs focal nerve dysfunction (what do they mean)

A

focal - localised lesion

a diffuse - widespread area of injury/damage

39
Q

What symptoms may be seen in global cognitive impairment?

A
  • disorientation and cognitive slowing
  • confusion and agitation
  • personality change
40
Q

What areas are involved in:

  • cortical dysfunction
  • subcortical dysfunction
  • brainstem dysfunction
  • cerebellar dysfunction
A
41
Q

What areas are involved in:

  • cognitive disorders
  • emotional/psychiatric disorders
  • movement disorders
  • pain
A
42
Q

Mention a few disorders related to brainstem

A
  • tinnitus and deafness
  • bulbar and pseudobulbar (related to cranial motor neurones)
  • nausea and vomiting
  • vertigo
  • double vision
  • sensory disturbance
  • autonomic dysfunction
  • quadriparesis (paresis = weakness)
  • possible ataxia
  • locked-in-syndrome
43
Q

What may be clinical signs of ataxia?

A
  • ipsilateral motor incoordination
  • slurring or scanning dysarthria

*scanning dysarthria = spoken words are broken down into the syllables

  • jerky eye movements
44
Q

How does ataxia may present on clinical examination?

A
  • dysmetria
  • dysdiadochokinesis
  • tremor
45
Q

Which nerve does that?

Hip flexion and knee extension

A

femoral n.

46
Q

What nerve does that?

Hip extension and knee flexion

A

Sciatic n.

47
Q

What nerve does that?

Ankle dorsiflexion and eversion

A

Common peroneal nerve

48
Q

Ankle plantarflexion and inversion

What nerve does that?

A

Tibial n.

49
Q

What disorders may cause peripheral neuropathy?

A
  • axonal polyneuropathy (diabetes, age)
  • demyelinating (GBS, chronic inflammatory demyelinating polyneuropathy)
  • mononeuritis multiplex (vasculitis, lymphoma)
50
Q

What disorders may cause peripheral neuropathy?

A
  • Myasthenia Gravis
  • Lambert-Eaton Myasthenic syndrome
51
Q

What disorders may cause myopathy?

A

inflammatory or genetic dystrophies