Clinical Neuroanatomy Flashcards

1
Q

Hyperacute presentation

  • time frame
  • possible atieology
A

Hyperacute presentation

  • instantenous, seconds
  • possible vascular pathology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Acute presentation

  • time frame
  • possible atieology
A

Acute

  • minutes to days
  • possible inflammatory, infectious pathology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Subacute presentation

  • time frame
  • possible atieology
A

Subacute

  • weeks to months
  • possible etiology: neoplasia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Chronic presentation

  • time frame
  • possible atieology
A

Chronic presentation

  • years
  • possible aetiology: genetic, degenerative
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

hemiparesis vs hemiplegia

A

Hemiparesis - weakness on one side of the body

Hemiplegia - paralysis of one side of the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Aphasia vs dysphasia

A

Aphasialoss of the ability to effectively communicate verbally due to a cognitive communication deficit. May be expressive, receptive or both

Dysphasia – cognitive communication impairment that does not prohibit verbal communication. May be expressive or receptive.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What’s anarthria and what’s dysarthria?

A

Anarthria/dysarthria – loss of/difficulty with verbal communication due to problems articulating words, for example, due to bulbar palsy or cerebellar disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What’s apraxia; what’s dyspraxia?

What are the types?

A

Apraxia/dyspraxia – loss of/difficulty planning to reach a given motor endpoint or perform sequenced activity.

May be (types):

  • ideational -> unable to sequence an imagined act e.g. ‘turn a key’
  • ideomotor -> unable to mimic an observed posture or movement
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What pyramidal tract connects?

A

Pyramidal corticospinal -> from motor cortex to lower motor neurons (via pyramid shaped tracts in brainstem)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Extrapyramidal tract

  • where does it go from?
  • what does it do?
A

Extrapyramidal tract

  • goes from basal ganglia

Primes motor cortex to produce activity and suppress the ones the areas that are not needed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does the cerebellum do in terms of movement?

A

Cerebellar area -> fine-tuning of activity; comparing planned with actual movements -> learned movements can be acted upon (performed)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does reticular formation do?

A

It is crucial for arousal and autonomic activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What gives rise to cranial nerves? Where anatomically is it located?

A

Cranial nuclei - locate in the brain stream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where do cranial nerves 1-2 arise from?

A

From the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where do cranial nerves 3-4 arise from?

A

Midbrain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where do cranial nerves 5-8 arise from?

A

Pons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Where do cranial nerves 9-12 arise from?

A

Medulla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What’s the role of Medial Longitudinal Fasciculus (MLF)?

A

Medial Longitudinal Fasciculus

It’s the main pathway that connects the vestibular and cochlear nuclei -> control the ‘gaze’ (oculomotor, trochlear and abducens)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Where does the spinal cord terminate?

A

T12 or L1 level with the conus _> which gives rise to cauda equina (lumbar spine houses cauda equina)

*cauda equina from T12 / L1 to the coccyx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Where is C8 nerve root located?

A

Between C7 and T1 vertebrae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Label the picture

22
Q

What’s input to the brain?

What’s the output?

A
  • Input - 5 senses, propriception
  • Output - motor and speech & autonomic regulation
23
Q

What brain lobes do optic radiations go through?

A

Parietal and temporal

24
Q

Where in the optic pathway do the projections from L and R visual fields go to?

A

Lateral Geniculate Nucleus

25
What are the parts of 'association cortex'?
**Association cortex**: * **prefrontal** -\> executive function * **posterior** -\> sensory
26
What are main (2) subcortical parts of the brain?
- thalamus - basal ganglia
27
What is the function of (in terms of movement): * basal ganglia * cerebellum
Basal ganglia -\> Initiation and amplification of movement Cerebellum -\> fine tuning
28
L and R Brain hemispheres and (3) areas/skills that they are responsible for
L -\> language, praxis (learnt motor movement), maths R -\> music, space, attention
29
**Midbrain** - cranial nerves in it - what centres are located there
**Midbrain** * CN III and IV * auditory and visual reflex centres
30
**Pons** - what cranial nerves are there - what does it do?
**Pons** ## Footnote - CN V - VIII - relay between cerebellum and cerebrum
31
**Medulla** - what cranial nerves are there - what centres does it contain?
**Medulla** ## Footnote - CN IX - XII - centres: cardiac, respiratory, vasomotor and autonomic
32
Front dermatomes (draw)
33
Back dermatomes (draw)
34
What is ***spondylosis***? \*complications
Spondylosis * degeneration of the spinal column ( any cause) * it refers to **spinal [osteoarthritis](https://en.wikipedia.org/wiki/Osteoarthritis)-\>** age-related wear and tear of the spinal column (most common cause) * mostly the vertebral bodies are affected -\> [neural foramina](https://en.wikipedia.org/wiki/Neural_foramen) and the [facet joints](https://en.wikipedia.org/wiki/Facet_joint) ([facet syndrome](https://en.wikipedia.org/wiki/Facet_syndrome)). \*If severe, it may cause pressure on the [spinal cord](https://en.wikipedia.org/wiki/Spinal_cord) or [nerve roots](https://en.wikipedia.org/wiki/Nerve) with subsequent [sensory](https://en.wikipedia.org/wiki/Sensory_system) or [motor](https://en.wikipedia.org/wiki/Motor_system) disturbances, such as [pain](https://en.wikipedia.org/wiki/Pain), [paresthesia](https://en.wikipedia.org/wiki/Paresthesia), [imbalance](https://en.wikipedia.org/wiki/Balance_(ability)), and [muscle weakness](https://en.wikipedia.org/wiki/Muscle_weakness) in the limbs.
35
What nerve supplies: Wrist and finger extensors
Radial nerve
36
What nerve supplies ## Footnote LOAF (lateral two lumbricals. opponens pollicis.abductor pollicis brevis.flexor pollicis brevis) muscles, grip, sensory lateral hand
Median nerve
37
What nerve supplies small muscles of hand and grip?
Ulnar n.
38
Diffuse vs focal nerve dysfunction (what do they mean)
focal - localised lesion a diffuse - widespread area of injury/damage
39
What symptoms may be seen in ***global cognitive impairment***?
- disorientation and cognitive slowing - confusion and agitation - personality change
40
**What areas are involved in:** - cortical dysfunction - subcortical dysfunction - brainstem dysfunction - cerebellar dysfunction
41
What areas are involved in: - cognitive disorders - emotional/psychiatric disorders - movement disorders - pain
42
Mention a few disorders related to brainstem
- tinnitus and deafness - bulbar and pseudobulbar (related to cranial motor neurones) - nausea and vomiting - vertigo - double vision - sensory disturbance - autonomic dysfunction - quadriparesis (paresis = weakness) - possible ataxia - locked-in-syndrome
43
What may be clinical signs of ataxia?
- ipsilateral motor incoordination - slurring or scanning dysarthria \*scanning dysarthria = spoken words are broken down into the syllables - jerky eye movements
44
How does ataxia may present on clinical examination?
- dysmetria - dysdiadochokinesis - tremor
45
Which nerve does that? Hip flexion and knee extension
femoral n.
46
What nerve does that? Hip extension and knee flexion
Sciatic n.
47
What nerve does that? Ankle dorsiflexion and eversion
Common peroneal nerve
48
Ankle plantarflexion and inversion What nerve does that?
Tibial n.
49
What disorders may cause ***peripheral neuropathy***?
- **axonal polyneuropathy** (diabetes, age) - **demyelinating** (GBS, chronic inflammatory demyelinating polyneuropathy) - **mononeuritis** **multiplex** (vasculitis, lymphoma)
50
What disorders may cause ***peripheral neuropathy***?
- Myasthenia Gravis - Lambert-Eaton Myasthenic syndrome
51
What disorders may cause ***myopathy***?
inflammatory or genetic dystrophies