Clinical Management of diabetes

Question 1

what ethnic groups are at high risk of developing diabetes

Answer 1

Afro-caribbean

Question 2

what happens to b-cell function over time in diabetes

Answer 2

Decline

Question 3

Symptoms of diabetes

Answer 3

Thirst
Polyuria/nocturia/incontinence in elderly
Tiredness
Blurred vision
Recurrent thrush
Recurrent infections
Feeling of unwell/poor concentration
Weight loss- yes in type1, not always type2
Mood changes
Micro or macro-vascular problems

Question 4

If in doubt if its type 1 or 2, what do you treat as

Answer 4

Type 1

Question 5

What is MODY caused by

Does MODY need insulin

Answer 5

Single gene defect altering beta cell function

not insulin dependent

Question 6

Diagnostic criteria for MODY

Answer 6

early onset diabetes
not insulin dependent
autosomal dominant inheritance

Question 7

major causes of insulin resistance in non obese patients

Answer 7

lipodystrophy cannot store far under skin result in ectopic fat

insulin receptor mutation

very rare other genetic causes