Clinical Laboratory In Modern Healthcare

Question 1

Laboratory tests are justified when the clinician knows before hand what to do with the result. T/F

Answer 1

True

Question 2

Testing for occult blood in stool is used for what cancer.

Answer 2

Colorectal cancer

Question 3

What is tested for in diabetes mellitus

Answer 3

Fasting plasma glucose

Question 4

Renal disease

Answer 4

Urine protein excretion

Question 5

High PSA(Prostate specific antigen)

Answer 5

Prostate cancer

Question 6

Elevations of conjugated bilirubin is accompanied with

Answer 6

Obstructive hepatitis

Question 7

Elevation in ammonia

Answer 7

Advanced liver disease

Question 8

Rise in creatinine and potassium level in urine is seen in

Answer 8

Renal failure

Question 9

Increased PCO2 is found in

Answer 9

Some pulmonary disease

Question 10

Match this tumour marker to their subsequent cancer.

1. CA-125
2. CEA
3. CA-19-9

Colon cancer
Ovarian cancer
Pancreatic cancer

Answer 10

1. Ovarian cancer
2. Colon cancer
3. Pancreatic cancer

Question 11

Primary hyperthyroidism is characterized by

Answer 11

Increased thyroxine

Decreased TSH

Question 12

Use of cardiac troponins are replacing CK-MB T/F

Answer 12

True

Question 13

What are the metrics used in diagnosing how good a test is

Answer 13

Diagnostic specificity
Diagnostic selectivity
Analytical specificity
Analytical selectivity

Question 14

Diagnostic sensitivity is

Answer 14

Showing how effective a test is in detecting individuals who have the disease in question.( percentage of true positive)

Question 15

Diagnostic specificity

Answer 15

Showing how effective a test is in detecting individuals who do not have the disease in question (percentage of true negative)

Question 16

When should you use a sensitive test

Answer 16

When you want to determine as many diseased person as possible(screening)

Question 17

When should u use a specific test

Answer 17

Confirmatory- aim is to exclude healthy people from unnecessary interventions

Question 18

Analytical sensitivity

Answer 18

can refer to the lowest detectable concentration of analyte

that can be measured with some defined certainty

Question 19

Analytical specificity

Answer 19

The extent to which other substances in the test system

interfere with measurement of the analyte of interest.