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3rd Year, 2nd Sem-PRELIMS > Clinical Correlation 2 > Flashcards

Clinical Correlation 2 Flashcards

1
Q

White Blood Cell Maturation

A

14 days

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2
Q

Stage number of Myeloblast

A

Stage 1

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3
Q

Stage number of Promyelocyte

A

Stage 2

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4
Q

Stage number of Myelocyte

A

Stage 3

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5
Q

Stage number of Metamyelocyte

A

Stage 4

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6
Q

Stage number of Band/Stab

A

Stage 5

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7
Q

Stage number of Mature Neutrophils, Eosinophils, and Basophils

A

Stage 6

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8
Q 
Highest NC (Nucleus-to-Cystoplasm) Ratio
(WBC Maturation)
A

Stage 1 - Myeloblast

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9
Q

Start of Primary Granules

WBC Maturation

A

Stage 2 - Promyelocyte

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10
Q

Start of Secondary Granules

WBC Maturation

A

Stage 3 - Myelocyte

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11
Q

Last stage capable of Cell Division / End of cell division

WBC Maturation

A

Stage 3 - Myelocyte

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12
Q

Start of Tertiary Granules

WBC Maturation

A

Stage 4 - Metamyelocyte

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13
Q

Indented nucleus or Kidney Bean-shaped

WBC Maturation

A

Stage 4 - Metamyelocyte

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14
Q

Earliest stage that appears in Peripheral Blood Smear

WBC Maturation

A

Stage 5 - Band/Stab

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15
Q

Sausage-shaped / Horseshoe-shaped

WBC Maturation

A

Stage 5 - Band/Stab

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16
Q

Contains 3 to 5 lobes of nucleus

WBC Maturation

A

Stage 6 - Mature Neu/Eo/Baso

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17
Q

Primary content of Neutrophil Granules

A 
Myeloperoxidase
Acid Hydrolase
Acid Phosphatase
Arylsulfatase
Elastase
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18
Q

Secondary content of Neutrophil Granules

A

Lactoferrin
Lysozyme
Collagenase

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19
Q

Tertiary content of Neutrophil Granules

A

Gelatinase

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20
Q

What are the Granulocytes?

A

(BEN)

Basophils
Eosinophils
Neutrophils

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21
Q

It is a Granulocyte that primary responds through bacterial infection

A

Neutrophils

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22
Q

It is a Granulocyte that contains a reddish granules / Bilobed nucleus

A

Eosinophils

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23
Q

It is a Granulocyte that responds to parasitic infections

A

Eosinophils

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24
Q

ASH Parasites

A

Ascaris
Strongyloides
Hookworm

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25
Q

It is a Granulocyte with Blue-black granules

A

Basophils

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26
Q

It is a Granulocyte that is responsible for allergic reactions

A

Basophils

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27
Q

It is an Agranulocyte that is responsible for viral infection. Also, the largest NC ratio in the WBC maturation.

A

Lymphocytes

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28
Q

Humoral-mediated immunity

A

B-cell

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29
Q

Cell-mediated immunity

A

T-cell

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30
Q

Responsible for tumor or cancer cells

A

Natural Killer (NK) Cell

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31
Q

It is an Agranulocyte and is the largest cell to appear in the Peripheral Blood Smear. Also, responsible for phagocytosis or destruction of your agent RBC

A

Monocytes

32
Q

A cell found in the Liver

A

Kupffer cells

33
Q

Kupffer cells

A
34
Q

A cell found in the Lung

A

Alveolar macrophage or Dust Cells

35
Q

A cell found in the Brain

A

Microglial cells

36
Q

A cell found in the skin

A

Langerhans cells

37
Q

A cell found in the spleen

A

Splenic macrophage

38
Q

A cell found in the connective tissue

A

Histiocytes

39
Q

A cell found in the bone

A

Osteoclast

40
Q

A cell found in the Synovium

A

Type A Cells

41
Q

A cell found in the placenta

A

Hofbauer cells

42
Q

A cell found in the kindey

A

Mesangial cells

43
Q

A cell found in the lymph nodes

A

Littoral cells

44
Q

Bone marrow is responsible for the release of what cells?

A

Progenitor cells (B-cells or immature cells)

45
Q

3 layers of Lymph Nodes

A
  1. Outer layer - Cortex (where B-cell resides)
  2. Inner layer - Paracortex (where T-cell resides)
  3. Innermost layer - Medulla (where Plasma Cell resides)
46
Q

Maturation site of progenitor T-cell happens in ________

A

Thymus

47
Q

Helper T-cell

A

CD4

((Hel4 T-cell))

48
Q

Cytotoxic / Suppressor Cells

A

CD8

((The S in Suppressor looks like 8))

49
Q

Neoplastic cells that develops INSIDE the Lymph nodes

A

Nodal Lymphoma

50
Q

Neoplastic cells that develops OUTSIDE the Lymph nodes

A

Extranodal Lymphoma

51
Q

Most common Non-Hodgkin’s B Lymphoma

A

Diffuse Large B-Cell Lymphoma (DLBCL)

52
Q

It is an Indolent or Slow growing type of Non-Hodgkin’s B Lymphoma

A

Diffuse Large B-Cell Lymphoma (DLBCL)

53
Q

Tumor markers for Diffuse Large B-cell Lymphoma

A

CD5, CD10, CD30

54
Q

Translocation of Chromosome 14 & 18

A

Follicular lymphoma

55
Q

Translocation resulting in BCL 2 genes

A

Follicular lymphoma

56
Q

Stimulates the growth and metabolism of neoplastic cells.

A

MYC genes

57
Q

Starry sky pattern

A

Burkitt lymphoma

58
Q

It is a highly aggressive type of Non-Hodgkin’s B Lymphoma

A

Burkitt lymphoma

59
Q

Happens when there is a translocation of chromosome 14 & 8 produces MYC genes.

A

Burkitt Lymphoma

60
Q

Most common Marginal zone lymphoma

A

Mucosal Associated Lymphoid Tissue (MALT)

61
Q

Soccer ball appearance with hairy cytoplasmic structure.

A

Hairy cell lymphoma

62
Q

Cytochemical stain used for Hairy Cell Lymphoma

A

(TRAP) Tartrate Resistance Acid Phosphatase

HCL (Positive); Pearl Prussian blue.

63
Q

The Adult T-cell Lymphoma is a type of Non-Hodgkin’s lymphoma that is caused by what virus?

A

(HTLV) Human T Lymphotropic Virus

64
Q

Cells seen in Mycosis Fungoides

A

Sezary cells

65
Q

Laboratory detection on Lymphoma

A
  • TRAP stain
  • CT scan
  • Chemotherapy treatment.
66
Q

Lymph nodes that are abnormal in size (e.g., greater than 1 cm) or consistency.

A

Lymphadenopathy

67
Q

T cell lymphoma of the skin

A

Mycosis fungoides

68
Q

Tumor markers for Classical Hodgkin’s Lymphoma

A

CD20 and CD15

69
Q

Classical Hodkin’s Lymphoma bone marrow stains

A
  • Wright’s stain
  • Perl Prussian blue
  • H & E stain.
70
Q

Classical Hodkin’s Lymphoma needle for collection

A

BM aspirate or University of Illinois

71
Q

It originated from germinal centers of Lymph node.

A

Lymphoid neoplasm

72
Q

Classical Hodgkin’s Lymophoma is exposed to what chemical?

A

Benzene

73
Q

A Hodgkin’s Lymphoma where T-cell originates

A

Nodular lymphocyte predominant hodgkin’s lymphoma

74
Q

Nodular lymphocyte predominant Hodgkin’s lymphoma Tumor markers

A

CD20 & CD45

75
Q

Transport system of Neisseria

A

Jembec system

76
Q

In Neisseria, all are Gram (-) diplococci except _______________

A

Neisseria elongate

77
Q

Kidney Bean-Shaped Neisseria

A

Neisseria gonorrhea

3rd Year, 2nd Sem-PRELIMS (2 decks)

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