Clinical Correlation 2

Question 1

White Blood Cell Maturation

Answer 1

14 days

Question 2

Stage number of Myeloblast

Answer 2

Stage 1

Question 3

Stage number of Promyelocyte

Answer 3

Stage 2

Question 4

Stage number of Myelocyte

Answer 4

Stage 3

Question 5

Stage number of Metamyelocyte

Answer 5

Stage 4

Question 6

Stage number of Band/Stab

Answer 6

Stage 5

Question 7

Stage number of Mature Neutrophils, Eosinophils, and Basophils

Answer 7

Stage 6

Question 8

Highest NC (Nucleus-to-Cystoplasm) Ratio
(WBC Maturation)

Answer 8

Stage 1 - Myeloblast

Question 9

Start of Primary Granules

WBC Maturation

Answer 9

Stage 2 - Promyelocyte

Question 10

Start of Secondary Granules

WBC Maturation

Answer 10

Stage 3 - Myelocyte

Question 11

Last stage capable of Cell Division / End of cell division

WBC Maturation

Answer 11

Stage 3 - Myelocyte

Question 12

Start of Tertiary Granules

WBC Maturation

Answer 12

Stage 4 - Metamyelocyte

Question 13

Indented nucleus or Kidney Bean-shaped

WBC Maturation

Answer 13

Stage 4 - Metamyelocyte

Question 14

Earliest stage that appears in Peripheral Blood Smear

WBC Maturation

Answer 14

Stage 5 - Band/Stab

Question 15

Sausage-shaped / Horseshoe-shaped

WBC Maturation

Answer 15

Stage 5 - Band/Stab

Question 16

Contains 3 to 5 lobes of nucleus

WBC Maturation

Answer 16

Stage 6 - Mature Neu/Eo/Baso

Question 17

Primary content of Neutrophil Granules

Answer 17

Myeloperoxidase
Acid Hydrolase
Acid Phosphatase
Arylsulfatase
Elastase

Question 18

Secondary content of Neutrophil Granules

Answer 18

Lactoferrin
Lysozyme
Collagenase

Question 19

Tertiary content of Neutrophil Granules

Answer 19

Gelatinase

Question 20

What are the Granulocytes?

Answer 20

(BEN)

Basophils
Eosinophils
Neutrophils

Question 21

It is a Granulocyte that primary responds through bacterial infection

Answer 21

Neutrophils

Question 22

It is a Granulocyte that contains a reddish granules / Bilobed nucleus

Answer 22

Eosinophils

Question 23

It is a Granulocyte that responds to parasitic infections

Answer 23

Eosinophils

Question 24

ASH Parasites

Answer 24

Ascaris
Strongyloides
Hookworm

Question 25

It is a Granulocyte with Blue-black granules

Answer 25

Basophils

Question 26

It is a Granulocyte that is responsible for allergic reactions

Answer 26

Basophils

Question 27

It is an Agranulocyte that is responsible for viral infection. Also, the largest NC ratio in the WBC maturation.

Answer 27

Lymphocytes

Question 28

Humoral-mediated immunity

Answer 28

B-cell

Question 29

Cell-mediated immunity

Answer 29

T-cell

Question 30

Responsible for tumor or cancer cells

Answer 30

Natural Killer (NK) Cell

Question 31

It is an Agranulocyte and is the largest cell to appear in the Peripheral Blood Smear. Also, responsible for phagocytosis or destruction of your agent RBC

Answer 31

Monocytes

Question 32

A cell found in the Liver

Answer 32

Kupffer cells

Question 33

Kupffer cells

Question 34

A cell found in the Lung

Answer 34

Alveolar macrophage or Dust Cells

Question 35

A cell found in the Brain

Answer 35

Microglial cells

Question 36

A cell found in the skin

Answer 36

Langerhans cells

Question 37

A cell found in the spleen

Answer 37

Splenic macrophage

Question 38

A cell found in the connective tissue

Answer 38

Histiocytes

Question 39

A cell found in the bone

Answer 39

Osteoclast

Question 40

A cell found in the Synovium

Answer 40

Type A Cells

Question 41

A cell found in the placenta

Answer 41

Hofbauer cells

Question 42

A cell found in the kindey

Answer 42

Mesangial cells

Question 43

A cell found in the lymph nodes

Answer 43

Littoral cells

Question 44

Bone marrow is responsible for the release of what cells?

Answer 44

Progenitor cells (B-cells or immature cells)

Question 45

3 layers of Lymph Nodes

Answer 45

1. Outer layer - Cortex (where B-cell resides) 2. Inner layer - Paracortex (where T-cell resides) 3. Innermost layer - Medulla (where Plasma Cell resides)

Question 46

Maturation site of progenitor T-cell happens in ________

Answer 46

Thymus

Question 47

Helper T-cell

Answer 47

CD4 | ((Hel4 T-cell))

Question 48

Cytotoxic / Suppressor Cells

Answer 48

CD8 | ((The S in Suppressor looks like 8))

Question 49

Neoplastic cells that develops INSIDE the Lymph nodes

Answer 49

Nodal Lymphoma

Question 50

Neoplastic cells that develops OUTSIDE the Lymph nodes

Answer 50

Extranodal Lymphoma

Question 51

Most common Non-Hodgkin's B Lymphoma

Answer 51

Diffuse Large B-Cell Lymphoma (DLBCL)

Question 52

It is an Indolent or Slow growing type of Non-Hodgkin's B Lymphoma

Answer 52

Diffuse Large B-Cell Lymphoma (DLBCL)

Question 53

Tumor markers for Diffuse Large B-cell Lymphoma

Answer 53

CD5, CD10, CD30

Question 54

Translocation of Chromosome 14 & 18

Answer 54

Follicular lymphoma

Question 55

Translocation resulting in BCL 2 genes

Answer 55

Follicular lymphoma

Question 56

Stimulates the growth and metabolism of neoplastic cells.

Answer 56

MYC genes

Question 57

Starry sky pattern

Answer 57

Burkitt lymphoma

Question 58

It is a highly aggressive type of Non-Hodgkin's B Lymphoma

Answer 58

Burkitt lymphoma

Question 59

Happens when there is a translocation of chromosome 14 & 8 produces MYC genes.

Answer 59

Burkitt Lymphoma

Question 60

Most common Marginal zone lymphoma

Answer 60

Mucosal Associated Lymphoid Tissue (MALT)

Question 61

Soccer ball appearance with hairy cytoplasmic structure.

Answer 61

Hairy cell lymphoma

Question 62

Cytochemical stain used for Hairy Cell Lymphoma

Answer 62

(TRAP) Tartrate Resistance Acid Phosphatase HCL (Positive); Pearl Prussian blue.

Question 63

The Adult T-cell Lymphoma is a type of Non-Hodgkin's lymphoma that is caused by what virus?

Answer 63

(HTLV) Human T Lymphotropic Virus

Question 64

Cells seen in Mycosis Fungoides

Answer 64

Sezary cells

Question 65

Laboratory detection on Lymphoma

Answer 65

- TRAP stain - CT scan - Chemotherapy treatment.

Question 66

Lymph nodes that are abnormal in size (e.g., greater than 1 cm) or consistency.

Answer 66

Lymphadenopathy

Question 67

T cell lymphoma of the skin

Answer 67

Mycosis fungoides

Question 68

Tumor markers for Classical Hodgkin's Lymphoma

Answer 68

CD20 and CD15

Question 69

Classical Hodkin's Lymphoma bone marrow stains

Answer 69

- Wright’s stain - Perl Prussian blue - H & E stain.

Question 70

Classical Hodkin's Lymphoma needle for collection

Answer 70

BM aspirate or University of Illinois

Question 71

It originated from germinal centers of Lymph node.

Answer 71

Lymphoid neoplasm

Question 72

Classical Hodgkin's Lymophoma is exposed to what chemical?

Answer 72

Benzene

Question 73

A Hodgkin's Lymphoma where T-cell originates

Answer 73

Nodular lymphocyte predominant hodgkin’s lymphoma

Question 74

Nodular lymphocyte predominant Hodgkin’s lymphoma Tumor markers

Answer 74

CD20 & CD45

Question 75

Transport system of Neisseria

Answer 75

Jembec system

Question 76

In Neisseria, all are Gram (-) diplococci except _______________

Answer 76

Neisseria elongate

Question 77

Kidney Bean-Shaped Neisseria

Answer 77

Neisseria gonorrhea