Clinical Conditions

Question 1

Pericarditis

Answer 1

inflammation of the pericardium

Question 2

Abscess

Answer 2

happens in solid tissue, a collection of liquefactive necrosis

Question 3

Blister

Answer 3

collection of exudate, strips exudate

Question 4

Lobar Pneumonia

Answer 4

caused by bacteria, worsening fever, hypoxaemia, dry cough and breathlessness

Question 5

Bacterial Meningitis

Answer 5

acute inflammation of the meninges can cause vascular thrombosis, reduce cerebral perfusion

Question 6

Chronic Granulatomas Disease

Answer 6

genetic defect in the NADPH, causes enhanced susceptability to bacterial infections
eg pneumonia

Question 7

Galactosaemia

Answer 7

excess NADPH consumed, compromised defences against ROS damage
build up of galactitol causing vomitting and renal failurew

Question 8

Paracetamol

Answer 8

causes enzymes to be saturated so build up of a toxic metabolite NAPQI