Clinical chem must to know Flashcards

1
Q

It is the daily monitoring of accuracy and precision

A

Internal QC

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2
Q

QC that has long-term accuracy

A

External QC

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3
Q

How long is the minimum availability for QC materials?

A

Minimum of 1 year

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4
Q

It is the dispersion of values from the mean

A

Standard Deviation

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5
Q

Relative magnitude of variability (%)

A

Coefficient of Variance

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6
Q

SD^2 and measure of variability

A

Variance

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7
Q

Means of 2 groups of data

A

T-test

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8
Q

SD of 2 groups of data

A

F-test

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9
Q

V mask and earliest identification of Trend

A

CUSUM Graph

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10
Q

Compare results from diff. lab

A

Youden/Twin plot

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11
Q

Graph for acceptable limits of variation

A

Shewhart Levey-Jennings Chart

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12
Q

Gradual loss of reliability

A

Trend

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13
Q

Cause of Trend

A

Deterioration of reagents (Systematic error)

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14
Q

Cause of Shift

A

Improper calibration (Systematic error)

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15
Q

One side or either side of mean

A

Shift

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16
Q

Degree of flatness or sharpness

A

Kurtosis

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17
Q

Precision is what type of error?

A

Random error

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18
Q

Accuracy is what type of error?

A

Systematic error

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19
Q

Distance between successive peaks (nm)

A

Wavelength

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20
Q

Measures light intensity in a narrower wavelength

A

Spectrophotometric Measurement

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21
Q

Measures light intensity w/o consideration of wavelength

A

Photometric Measurement

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22
Q

Lamps that has UV light

A

Deuterium lamp
Mercury Arc
Xenon Lamp
Hydrogen lamp

23
Q

IR (Infrared light)

A

Merst glower

Globar (Silicone carbide)

24
Q

Most common cause of linearity

A

Stray light

25
Q

Most commonly used monochromator

A

Diffraction gratings

26
Q

Prevents stray light

A

Nickel sulfate

27
Q

Anti-stray light

A

Cutoff filter

28
Q

Most commonly used cuvet

A

Alumina silica glass cuvet

29
Q

Simplest detector for filter photometers

A

Barrier layer cell/ photocell/ photovoltaic cell

30
Q

Most common type of tube in analytical chem

A

Photomultiplier tube

31
Q

Most common type of tube

A

Photomultiplier tube

32
Q

Formula of Absorbance

A

A = 2-log%T

33
Q

Measure light absorbed by atoms dissociated by heat

A

Atomic Absorption Spectroscopy

34
Q

Molecules migrate through a pH gradient

A

Isoelectric focusing

35
Q

It detects DNA

A

Southern blot

36
Q

It detects RNA

A

Northern blot

37
Q

It detects proteins

A

Western blot

38
Q

It is used as screening test for drugs

A

Thin Layer Chromatography

39
Q

Gold standard for drug testing

A

Gas Chromatography/Mass Spectrometry (GS/MS)

40
Q

Major disadvantage of Fluorometry

A

Quenching

41
Q

6x stronger than Borosilicate

A

Corex (corning)

42
Q

Can be heated for 900C

A

Vycor (corning)

43
Q

It has etched rings on top of pipet

A

Blowout

44
Q

A transfer pipet for non-viscous fluid; self-draining

A

Volumetric

45
Q

A transfer pipet for viscous fluid; w/ etched ring

A

Ostwald folin

46
Q

A transfer pipet w/o consideration of a specific volume

A

Pasteur

47
Q

w/ graduations to the tip (blowout)

A

Serological

48
Q

w/o graduations to the tip (self-draining)

A

Mohr

49
Q

TC pipets: (does not disperse exact volume)

A

Salih-Hellige pipet
Lang-levy pipet
RBC and WBC pipet
Kirk and Overflow pipet

50
Q

Cleaning solution for glasswares

A

Acid Dichromate ( H2SO4 + K2Cr2O4 )

51
Q

Examples of centrifugal analyzer

A

“RICC”
RotoChem
IL Monarch
Cobas-Bio (Roche)
CentrifiChem

52
Q

Most popular analyzer

A

Discrete analyzer

53
Q

Examples of Thin-Film Analyzers

A

“KV2(75)”
Kodak Ektachem
Vitros 750XRC
Vitros 550XRC

54
Q

Increased in Hemolysis

A

“KLA