Clinical Chem Final Exam Flashcards
True or False:
The Hemoglobin A1C test measures the avg. amount of blood glucose over a 3 month period?
True
What does the GTT assist in the diagnosis of?
Diabetes
What is the xylose tolerance test primarily tested for?
Absorption ability of the small intestine
What is the 2 hour PC glucose test?
A test where blood is collected 2 hours after finishing the meal
What is the next immediate step after drawing blood for arterial/venous blood gases?
The specimen is put on ice and tested STAT
What is the dose of glucose for the GTT?
75 grams of glucose in 300 ml of solution
What specimens are required for OGTT and GTT?
Urine and blood
What do beta cells produce and what is their function?
They produce insulin when blood glucose is high
What do alpha cells produce and what is their function?
They produce glucagon hormone when blood glucose is low
Where can CPK/CK be found?
Brain, muscles, heart
What specimen is required for GGT?
Serum
What will be elevated in a patient with hepatitis?
Bilirubin
What enzymes will be elevated in a patient with acute MI?
LDH, CPK, AST
What enzymes are part of the cardiac enzyme profile?
LDH, CPK, AST
What enzymes are part of the liver enzyme profile?
ALP, ALT, GGT
What diseases or disorders is the lipoprotein electrophoresis used to detect?
Coronary Heart Disease, Atherosclerosis, Cardiovascular disorders
What is the clinical significance of LDH?
Cancers, leukemia, heart failure, embolism
What should a patient do for an accurate cholesterol test?
Fast overnight
Follow a normal diet one week before the test
No alcohol
No lipid lowering drugs
What components are found in plasma?
Cholesterol, calcium, glucose, fibrinogen
What is buffer?
Weak acid/weak base with salt
Which test should not be performed on a serum sample?
Clotting factor
Acid Phosphatase is an enzyme which is elevated in?
Prostatic cancer
What are the end products of protein digestion?
Amino acids
What are amino acids transformed into?
Ammonium ions
Define ammonia
Produced from leftover amino acids, it’s a waste that is excreted through the liver