Clinical Flashcards

1
Q

CFs of fat necrosis

A
  • Firm lump eventually shrinks in size until resolution
  • Difficult to differentiate from other causes of breast lump
  • ~40% will describe Hx of trauma
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2
Q

Rx of mastalgia

A
  • Reassurance -> no Ca
  • Supportive bra
  • Reduce dietary fat + caffeine
  • Severe mastalgia affecting ADLs =-> estrogen suppression
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3
Q

Approach to nipple d/c

A
  • Spontaneous vs. squeezing @ nipple
  • Single vs. multiple duct d/c (check x1 duct d/c for Hb)
  • Bloody d/c requires triple assessment (5-10% = Ca)
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4
Q

XR features of Ca on mammography

A
  • Microcalcifications within / without lesions

- Areas of increased density or irregularity

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5
Q

Most common presenting breast Sx

A
  • Breast lump / lumpiness 36%
  • Painful breast lump 33%
  • Mastalgia 17.5%
  • Nipple d/c 5%
    Nipple retraction 3%
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6
Q

Most important part of clinical assessment

A
  • Pt’s age -> increasing age -> increased breast Ca incidence
  • In younger pt’s the pathology is much more likely to be benign
  • Duration of Sx
  • Ca = slow
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7
Q

Screening of high risk females

A
  • <50yo then mammography + MRI
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8
Q

Triple assessment

A
  1. Clinical exam
  2. Imaging (US +/- mammogram)
  3. Bx - core vs. FNA
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9
Q

Benign breast conditions <25yo

A

Stromal = juvenile hypertrophy

Lobular = fibroadenoma

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10
Q

Benign breast conditions 25-40

A

Cyclical activity = cyclical mastalgia, cyclical nodularity (diffuse/local)

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11
Q

Benign breast conditions 30-55

A

Involution

Lobular = palpable cysts

Ductal = ductal ectasia

Stromal = sclerosing lesions

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12
Q

CFs of ductal ectasia

A
  • Nipple d/c = chessy

- Nipple retraction = slit-like (in contract to breast Ca where the whole nipple is pulled in)

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13
Q

CFs of ductal papilloma

A
  • Nipple d/c = serous or blood-stained
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14
Q

Principles of breast infection

A
  1. Give appropriate Abs early to reduce incidence of abscess formation
  2. If an abscess is suspected -> confirm presence of pus prior to aspiration
  3. Excl. breast Ca using imaging + consider core Bx in any inflamm. lesions NOT improving w/ ABx
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15
Q

ABx Rx of breast infection

A
  • Lactating = flucloxacillin

- Non-lactating = augment DF

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16
Q

Staging of breast Ca (T)

A

T1 = <2cm

T2 = 2-5cm

T3 = >5cm

T4a = involves chest wall

4b = involvement of skin

4c = a + b

4d = inflamm.

17
Q

Staging of breast Ca (N)

A

N0 = no LNs

N1 = mobile LN on ipsilateral side

N2 = fixed LN on ipsilateral side

N3 = internal thoracic LN on ipsilateral side (rarely detectable)

18
Q

Staging of breast Ca (M)

A

M0 = no mets

M1 = distant mets incl. supraclavicular nodes

19
Q

Most common location of breast Ca

A
  • Upper outer quadrant
20
Q

Rx of DCIS

A

Low grade = WLE

High grade = WLE + adjuvant radiotherapy

21
Q

Possible adjuvant hormonal therapy

A
  1. Oophrectomy - surgical, radiation, chemical (goserelin)
  2. Tamoxifen -> competitive partial oestrogen receptor antagonist
  3. Aromatase inhibitors -> anastrozole / letrozole
22
Q

Cx of breast surgery

A
  1. Haematoma
  2. Infection

If performing axillary clearance

  1. Thoracodorsal nerve (C6-8) = atrophy of lat dorsi, prominent scapular
  2. Long thoracic nerve (C5-7) = winged scapula
  3. Intercostobrachial nerve = loss of sensation to upper / inner aspect of arm
  4. Lymphoedema