Clinical Flashcards
1
Q
What is coeliac disease?
A
Chronic inflammatory condition of the small bowel
Through food intolerance/autoimmunity to gluten
2
Q
What is steatorrhoea?
A
Excess fat in the faeces
3
Q
Classic presentation of coeliac disease?
A
Malabsorption, weight loss, steatorrhoea
4
Q
Tests for celiac disease?
A
IgA - Antibody test
Gold standard is upper GI endoscopy
5
Q
What is it from gluten that causes celiac disease?
A
Gliadin originally and then endomysial, then tissue transglutaminase
6
Q
What cells cause the reaction to gliadin (gluten) in celiac disease?
A
CD4 T cells
7
Q
What condition can celiac disease lead to?
A
T cell lymphoma
