Clinical

Question 1

What are normal values for a lipid panel?

Answer 1

Total cholesterol less 200mg/dL
LDL less than 130 mg/dL
HDL greater than 39 mb/dL
TAG less than 150mg/dL

Question 2

What is the primary target for lipid therapy?

Answer 2

LDL b/c its the major athrogenic lipoprotein

Question 3

Your patient has a TAG level of 509mg/dL what disease are they at increase risk for, and what would you recommend in addition to drug treatment?

Answer 3

pancreatitis

weight loss- can decrease TAG levels by 22% increase HDL slightly

Question 4

Define what a high vs moderately intense statin therapy means.

Answer 4

High-daily dose lowers LDL cholesterol by at least 50%

Moderate-daily dose lowers LDL cholesterol by 30-50%

Question 5

What’s the primary determinant between prescribing a high vs moderate intensity statin?

Answer 5

If 10 year risk calculation of athrerosclerotic CVD is < or > than 7.5%

Question 6

A 50 y/o african american man is evaluated during a routine wellness exam. He is a non smoker and does not have diabetes. His blood pressure is 144/84mmHg. Total cholesterol is 150mg/dL, TAG 220 mg/sL, HDL 37mg/dL, LDL 100mg/dL. His calculated 10 year risk of atherosclerotic CVD is 9% what should you do?

A) no meds needed
B) start fibrates
C) Start high intensity statin therapy
D) Start low intensity statin therapy
E) Start therapeutic lifestyle changes

Answer 6

C is correct. Assume that lifestyle modification has already been advised. This is based on is 10 risk calculation. He has no diabetes, and a LDL below 190mg/dL but his other risk factors make him a candidate for high dose statin therapy.

Question 7

How much can lifestyle modification improve your HDL levels?

Answer 7

increase by 1-4 mg/dL