Clinical Flashcards

1
Q

There is a sick patient in Resus. How do you approach this case?

A

—This is a sick/frail/at risk patients who I am concerned about.
—I would do a rapid assessment of the patient’s stability and decide where the best place will be to stabilise/optimise/resuscitate them whilst simultaneously mobilising team X/Y/Z
—My priorities are…

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2
Q

What is pre-eclampsia?

A

Multisystem disorder of pregnancy from inadequate trophoblastic invasion
Pre-eclampsia is a disorder of pregnancy defined by:
—New onset BP >140/90 after 20 weeks gestation
Plus one of:
—Proteinuria
—Organ dysfunction
—Placental dysfunction

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3
Q

What is carcinoid syndrome?

A

Carcinoid syndrome is a rare condition seen in patients with the neuroendocrine carcinoid tumour where the tumour/metastasis is outside of the hepatic portal system.
Its typical features involve: flushing, diarrhoea and bronchospasm as well as R heart disease

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4
Q

You are asked to deal with an emergency. What will you do?

A

From the information I have, I suspect…

I will call for assistance and assign roles (+/-QRH)
I will apply specific and supportive measures:
—Secure airway
—Control ventilation
—Ensure cardiovascular stability

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5
Q

What is COPD?

A

Chronic respiratory condition with classical features of cough, dyspnoea, sputum production often in patients with risk factors
Classified using the GOLD criteria

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6
Q

What are some causes for raised temperature under GA?

A
Sepsis
Malignant Hyperthermia
Neuroleptic Malignant Syndrome
Thyroid storm
Ecstasy use
Serotonin syndrome
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7
Q

What are the considerations for pre-op assessment for thoracic surgery?

A

—Post op MI risk
—Thoracosore (uses 9 variables to predict surgical mortality)(Age,Sex,ASA,Performance status, Severity of dyspnoea, Priority of surgery, Extent of resection, Diagnosis (malignant etc), Comorbidity)
—Resp function & post op dyspnoea

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8
Q

What is autism?

A
Neuropsychiatric disorder:
Triad of difficulty with :
-imagination
-communication
-interaction
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9
Q

What is Eisenmenger’s Syndrome?

A

Communication between the systemic and pulmonary circulation with pulmonary hypertension causing a right-to-left shunt

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10
Q

What is rheumatoid arthritis?

A

Chronic multisystem autoimmune disease of unknown cause

Results in symmetrical inflammatory polyarthritis with extra-articular features

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11
Q

What is a phaeochromocytoma?

A

Functionally active, catecholamine-secreting neuroendocrine tumour of chromaffin cells usually in adrenal medulla.
Secrete any combination of noradrenaline/adrenaline/dopamine

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12
Q

What is pyloric stenosis?

A

Most common surgical condition in <6month old

Hypertrophy of pyloric muscle causing gastric outflow obstruction, vomiting, metabolic alkalosis

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13
Q

What do we mean by conscious sedation?

A

A level of sedation where the patient remains conscious, retains protective reflexes and can respond to commands but allows sufficient anxiolysis and hypnosis for procedure

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14
Q

What is cerebral palsy?

A

A group of permanent movement and posture disorders that limit activity due to acquired pathology within the developing brain in the prenatal/neonatal/early infant period.

It is a clinical description based on an assessment of development and not a disease

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15
Q

What are the Echo criteria for Aortic Stenosis?

A
—Valve area:
Mild >1.5cm
Moderate 1-1.5cm
Severe <1cm
Critical <0.6cm
—Mean gradient:
Mild <25mmHg
Moderate 25-40mmHg
Severe 40-50mmHg
Critical >50mmHg

—Peak gradient:
Mild <40mmHg
Moderate 40-65mmHg
Severe >65mmHg

—Jet velocity:
Mild <3m/s
Moderate 3-4m/s
Severe >4m/s

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16
Q

What is your technique for an awake fibreoptic intubation?

A

DAS guidelines: Sedation, Topicalisation, Oxygenation, Perform (meh)
Sedation: Remi, x2 people, anti-sialogogue
Oxygenation: HFNO
Topicalisation:
—Cophenylcaine to nose
—10% lidocaine up to 20 sprays to base of tongue, back of throat, gargle (9mg/kg)
—x3ml of 2% lidocaine for spray as you go to cords etc
Perform: good positioning, ergonomics

2 point check:
—CO2
—view through scope - carina/trachealis

17
Q

What crises can occur in sickle cell patients?

A

Vaso-occlusive
Splenic
Bone marrow - either haemolytic or aplastic (parvovirus B19)

18
Q

What is the triad of tetanus?

A

—Rigidity
—Muscle spasm
—Autonomic dysfunction

Tetanospasmin inhibits GABA release

Treat with sedation/muscle relaxation (Propofol, Benzos, NMBDs, Mg, clonidine) plus general ICU measures

19
Q

What do we mean by the term ‘hypotensive anaesthesia’?
When might we use it and how?
Are there any contraindications?

A

-Reduction of MAP by up to 30% of patient’s normal

-Mainly in ENT (FESS, bimaxilliary osteotomy etc)
-Use of:
—Anaesthetic agents: REMI, TIVA
—Drugs acting on SVR: GTN, SNP, Hydralazine, Alpha blockers
—Drugs acting on CO: Beta blockers, Mg, clonidine

-IHD, HTN (uncontrolled), DM, anaemia, Sickle cell, CVA, renal impairment

20
Q

What risks calculator tools are there?

A
ACS NSQIP (elective)
Lee’s CRI
NELA (emergency); PPOSSUM, VPOSSUM
SORT
Frailty scores

EuroSCORE II
Thoracoscore
Nottingham Hip Fracture?

21
Q

What are the components of Lee’s CRI?

A
High risk surgical procedure
IHD
CCF
CVA
Insulin
High Cr >177
22
Q

What is frailty?

A

A state of increased vulnerability to poor resolution of homeostasis after a stressor event

23
Q

How does DKA occur?

A
  • In times of low insulin, free fatty acids broken down
  • Build up of Acetyl-CoA, which is converted to ketone bodies in the liver
  • Ketone bodies are acid in the body, buffered until capacity exceeded and metabolic acidosis occurs
24
Q

What are some causes of hypoventilation?

A

Central drive:
—Drugs - opiates, anaesthesia
—Stroke/trauma to brainstem/Resp Centre
—Spinal cord injury (high)

Neuromuscular disorders (weakness):
—Infection - Guillain Barre, botulism, polio
—Muscular dystrophy
—Myasthenia Gravis

Chest wall problems (restrictive):
—Trauma - flail segment
—Kyphoscoliosis

Lung problems:
—ARDS
—Asthma (airways resistance)
—LV failure
—Airway obstruction
Other:
—Pain
—Diaphragmatic splinting
—Obesity
—?OSA
25
Q

What is asthma?

A

Chronic inflammatory disease of airway causing reversible airway obstruction when triggered in susceptible people
Mediated by mast cells, eosinophils & T lymphocytes