Clin Med - Endocrine Part 1 Flashcards

1
Q

Endocrine glands secrete….

A

hormones that act on target cells

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2
Q

Endocrine glands are controlled by…

A

negative feedback mechanisms

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3
Q

Nonapeptide hormones released from pituitary gland

A
  • Growth hormone
  • Arginine vasopressin (ADH)
  • Prolactin
  • Oxytocin
  • (melanocyte stimulating hormone)
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3
Q

Endocrine glands hormones

A
  • Parathyroid glands
  • Pancreas
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4
Q

Tropic hormones released by pituitary gland

A
  • Thyroid gland
  • Adrenal cortex
  • Reproductive glands
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5
Q

Hormones secreted from adrenal medulla

A
  • epinephrine
  • norepinephrine
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5
Q

Hormones secreted from adrenal cortex

A
  • cortisol
  • aldosterone
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5
Q

Functions of cortisol

A
  • Manages how your body uses CHOs, fats, and PROs
  • Keepsinflammationdown
  • Regulates yourBP
  • Incrblood sugar(glucose)
  • Controls yoursleep/wake cycle
  • Boosts energy so you can handle stress & restores balance afterward
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6
Q
A
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7
Q

CRH triggers…

A

the pituitary gland to release ACTH

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7
Q

Hypothalamus releases…

A

CRH
- corticotropin releasing hormone

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8
Q

Function of ACTH

A

causes adrenal cortex to release cortisol

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9
Q

Primary adrenal insufficiency (Addison’s Dz) higher incidence of all-cause mortality form…

A
  • CV dz, malignancy & infx
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10
Q

Spectrum of assoc dz may be seen in adulthood:

A
  • Hypogonadism
  • hypothyroidism
  • pernicious anemia
  • alopecia
  • vitiligo
  • hepatitis
  • malabsorption
  • Sjögren syndrome
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10
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A
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11
Q

Toxic Multinodular Goiter (Plummer’s Dz) DDx

A
  • Goiter
  • Graves Dz
  • Hashimoto Thyroiditis
  • Nontoxic Goiter
  • Papillary Thyroid Carcinoma
  • Riedel Thyroiditis
  • Thyroid Nodule
  • Thyroiditis, Subacute
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11
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12
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13
Q

Diffuse Toxic Goiter (Graves Dz) DDx

A
  • Acute hemorrhage into a thyroid cyst, nodule, or neoplasm
  • Thyroiditis (early)
    –> Infectious thyroiditis
    –> Radiation-induced thyroiditis
    –> Trauma- or palpation-induced thyroiditis
    –> Riedel or fibroid thyroiditis
    –> Acute suppurative thyroiditis
  • Toxic thyroid adenoma
  • Toxic multinodular goiter
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14
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14
Q

Autoimmune Thyroiditis (Hashimoto) DDx

A
  • Acute hemorrhage into a thyroid cyst, nodule, or neoplasm
  • Infectious thyroiditis
  • Radiation-induced thyroiditis
  • Trauma- or palpation-induced thyroiditis
  • Riedel or fibroid thyroiditis
  • Graves thyrotoxicosis
  • Toxic thyroid adenoma
  • Toxic multinodular goiter
  • Acute suppurative thyroiditis
15
Q

Subacute (Painful) Thyroiditis DDx

A
  • Acute hemorrhage into a thyroid cyst, nodule, or neoplasm
  • Infectious thyroiditis
  • Radiation-induced thyroiditis
  • Trauma- or palpation-induced thyroiditis
  • Riedel or fibroid thyroiditis
  • Graves thyrotoxicosis
  • Toxic thyroid adenoma
  • Toxic multinodular goiter
  • Acute suppurative thyroiditis
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19
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DDx for Primary Adrenal Insufficiency (Addison’s Dz): Hyperpigmentation

A
  • bronchogenic carcinoma
  • ingestion of heavy metals (eg, iron, silver)
  • Peutz-Jeghers syndrome
  • vitiligo
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