Clin Lab - Endocrine Diagnostics Overview Flashcards

1
Q

Draw the Endocrine system subdivisions

A

DONE

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2
Q

What can go wrong?
three major categories

A
  1. Production issues by gland
  2. Regulation issues
  3. Hormone from another sourse
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2
Q

Production issues by gland examples.

A
  • overproduction of hormone
  • underproduction of hormone
  • inappropriate release of hormone
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3
Q

Hormone from another source examples.

A
  • endogenous source
  • (exogenous source)
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3
Q

Regulation issues examples.

A
  • loss of responsiveness to hormone
  • loss of negative feedback
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3
Q

Easiest ways to measure endocrine function

A
  • target organ output
  • endocrine gland hormone e
  • pituitary gland hormone
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4
Q

Hard way to measure endocrine function

A

hypothalamus factors

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4
Q

Hypofunction
Disorder: Primary (gland issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: decr
Pituitary gland SH level: incr

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4
Q

Define hypofunction

A

decreased target organ output

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4
Q

Hypofunction
Disorder: 2ndary (pituitary issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: decr
Pituitary gland SH level: decr

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4
Q

Hypofunction
Disorder: Tertiary (hypothalamus issue - rare)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: decr
Pituitary gland SH level: decr

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4
Q

Hypofunction
Disorder: Target organ issue (rare)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: incr
Pituitary gland SH level: incr

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4
Q

Define Hyperfunction

A

increased target organ action

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4
Q

Hyperfunction
Disorder: Primary (gland issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: incr
Pituitary gland SH level: decr

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4
Q

Hyperfunction
Disorder: 2ndary (pituitary issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: incr
Pituitary gland SH level: incr

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4
Q

Hyperfunction
Disorder: Tertiary (hypothalamus issue - rare)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: incr
Pituitary gland stimulating hormone level: incr

4
Q

Hyperfunction
Disorder: Exogenous source - endocrine hormone mimic
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: decr
Pituitary gland stimulating hormone level: decr

4
Q

Hyperfunction
Disorder: Exogenous source - pituitary stimulating hormone mimic
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:

A

Endocrine gland hormone level: incr
Pituitary gland stimulating hormone level: decr

5
Q

List endocrine organs

A
  • hypothalamus
  • pituitary gland
  • thyroid
  • parathyroid
  • adrenal glands
  • pancreas
  • ovaries/testes
6
Q

List endocrine related organs & their homrone

A
  • skin (calcitriol)
  • heart (BNP)
  • stomach (gastrin, somatostatin, leptin)
7
Q

Describe a primary disorder

A

the endocrine organ itself is affected

8
Q

Describe a secondary disorder

A

the pituitary gland is affected & releasing too much/too little of the hormone(s) that influences the endocrine organ

9
Q

Describe a tertiary disorder

A

the hypothalamus is affected & releasing too much/too little of the releasing factor(s) that influence the pituitary (rare!)

10
Q

Function of the anterior pituitary

A

releases prolactin & growth hormone that act on target tissues, not another endocrine gland

11
Q

Function of the posterior pituitary

A

stores & releases ADH & oxytocin that actin on target tissues

12
Q

Which endocrine glands are not under the influence of the hypothalamus or pituitary?

A
  • pancreas
  • parathyroid
13
Q

Draw endocrine system chart

A

DONE

14
Q

Diagnostic pattern for primary issue

A
  • lab findings are opposite
  • endocrine low/pituitary high, or vice versa
15
Q

Diagnostic pattern for secondary issue

A
  • lab findings are similar
  • both low or both high
16
Q

With endocrine issues, first testing does what?

A

establish that there is an imbalance & in which direction

17
Q

With endocrine issues, second testing does what?

A

distinguish primary from non-primary causes

18
Q

With endocrine issues, 3rd/further testing does what?

A

evaluate cause