Clear Cell Chondrosarcoma

Question 1

Clear cell histology

Answer 1

Chondrocytes with clear, vacuolated cytoplasm in chondroid matrix

Question 2

Clear cell chondrosarc location

Answer 2

Epiphysis

Question 3

Clear cell chondrosarc radiographic appearance

Answer 3

Mixed lytic/sclerotic lesion, paucity of calcifications; no “popcorn calcifications” typical of regular chondrosarcoma