Classification Of Virus Flashcards
Viruses are?
Obligate Intracellular parasites
Viruses are the _______ infectious agents ranging from ___to ___ nm in diameter
Smallest
20-300
Viruses contain only one kind of ______
Nucleic acid
Dna/ RNA but not both
__________ contains information to initiate and complete an infectious cycle within a cell
Viral genome
How are viruses transmitted from one host to another and establish themselves so survival is ensured
Viral Genome
What are the 5 classifications of virus genome properties
Type of nucleic acid
Size of genome
Strandedness; linear or circular
Sense (positive, negative, ambisense)
Segments (number & size)
Classification of viral morphology include
Size
Shape
Type of symmetry
Physio chemical properties of viruses (reliable modern satisfactory parameters) include
Molecular mass
Buoyant density
pH stability
Thermal stability
Susceptibility to physical and chemical agents (Ether & detergents)
Crude classification of viruses uses parameters like
Host
Other criterias for virus pathogenicity are
GIT
CNS
Ecological criteria for classifying virus:
Mode of transmission
Vectors
Reservoirs
What is the name of global committee for viral nomenclature
ICTV
INTERNATIONAL COMMITTEE ON TAXONOMY OF VIRUSES
Suffixes of
Order
Family
Sub family
Specie
VIRALE
VIRIDAE
VIRINAE
VIRUS
How many families of DNA and RNA families are recognized in humans
7 DNA families
14 RNA families
Classify Ebola Virus
Order: Mononegavirales
Family:Filoviridae
Genus: Ebolavirus
Species: Ebolavirus zaire, Ebola Sudan, Ebola Tai forest, Ebola Bundibugyo
Classify Herpes Simplex
• Order: Herpesvirale
• Family: Herpesviridae
• Subfamily: Alphaherpesvirinae
•Genus: Simplexvirus
• Species: Herpes Simplex virus type 1
What are Arbo viruses
ARthropod BOrne Viruses
All DNA viruses are double stranded except
PARVO Virus
Circular DNA viruses are
Papilloma
Polyoma
Hepadna
The biggest DNA virus that replicates in the cytoplasm is
POX VIRIDAE
Hepatitis B virus is in which family
Hepadna viridae
Hepatitis E virus is in family
Calci VIRIDAE (rna)
Ebola virus and Yellow fever virus belong to families
Filoviridae
Flaviviridae
An example of ReoViridae is
Rota Virus
Retro viridae is unique in that
Replication is unique: the horizon contains a reverse transcriptase enzyme that produces a DNA copy of the RNA genome
Eg HIV, HTLV
All rna viruses are single stranded except
Reo viridae
Which dna virus takes its envelope from the nuclear membrane
Herpes Viridae
Pox symmetry
Complex
Segmented RNA viruses include
Orthomyxo Influenza
Reo Viridae
[Arena
Bunya]
Enveloped DNA Viruses are
Hepadna
Herpes
Pox
Do viruses undergo binary fission
No
All helical viruses are
Enveloped
+ve sense rna virus include
Calici
Picorna
Corona
Flavi
Toga
Retro viridae
Negative: Old Pete Rabid dog FILO feeds BUNYo in ARENA
3 non enveloped rna virus
Picorna
Calici
Reo
All rna virus undergo replication in the cytoplasm except 2
Retro
Orthomyxo viridae
In Dna/rna which replicates more easily
Rna
Which rna virus family is ambisense
Arena virus
Example of parvoviridae
Human parvovirus B19
genus: Parvovirus, Erythrovirus, Dependovirus
Example of polyoma virus
JC virus
BK virus
Eg of Papillomaviridae
Human papillomavirus (over 100 genotypes)
Adenoviridae eg
Human adenoviruses (51 types)
genus:Mastadenovirus e.g Human Adenovirus(several serotypes)
Hepadnaviridae
Hepatitis B virus
Genus: Hepadnavirus e.g Hepatitis B virus
Herpesviridae
Varicella-Zoster virus, Human Cytomegalovirus
Genus: Simplex virus,
Varicello virus, Cytomegalovirus,
Roseolovirus
,Lymphocrypto virus
POxviridae
Small pox
genus: orthopox,suispox,avipox,mollusci pox
List the positive sense rna dividing it between
Naked & Enveloped
Naked:
Caliciviridae
Picornaviridae
Enveloped:
Coronaviridae
Flaviviridae
Togaviridae
Retroviridae
Negative sense rna
Bunya
Arena
Fill
Paramyxo
Orthomyxo
Arenaviridae-
genus: Arenavirus e.g Lassa , Mopeia, Junin, Machupo
Astroviridae-
genus:Astrovirus
Bunyaviridae-
genus: Bunyavirus, Nairovirus, Hantanvirus, Phlebovirus
Caliciviridae-
genus:, Norwalk, Hepatitis E virus
Coronaviridae-
genus:Coronavirus, SARS virus
Filoviridae-
genus:Ebola, Marburg
Flaviviridae-
genus: Yellow fever virus
dengue virus
West nile virus
Hepatitis C Virus
Orthomyxoviridae-
genus:
Influenza virus A,B,C
Paramyxoviridae-genus:
Parainfluenza,
Human metapneumovirus
Mumps
Measles
respiratory syncytial viruses
Picornaviridae-genus:
Enterovirus
,Hepatovirus,
Rhinovirus
Reoviridae-
Genus: Rotavirus
Retroviridae-
genus:Lentivirus,
(spp – HIV)
HTLV
Rhabdoviridae-
genus: Rabies virus, Lyssavirus, Vessiculovirus
Togaviridae-
genus: Alphavirus (Chikungunya), Rubivirus (Rubella virus)
Most viruses derive their envelope from the cell’s outer membrane with the exception of
Herpesviruses
Derive theirs from cell’s nuclear membrane
All RNA viruses are single stranded except
Reoviridae ds
Segmented genome are found in
Reo virus ds
Bunya
Orthomyxo
Paramyxovirus