Classification of Anemia Flashcards

1
Q

MCV is greater than 96 fl. MCHC is normal

A. . Microcytic hypochromic anemia
B.Macrocytic normochromic anemia
C. Normocytic normochromic anemia

A

B.Macrocytic normochromic anemia

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2
Q

MCV is less than 80 fl., decreased Hgb,
MCHC is less than 32%, must be addressed immediately

A. Microcytic hypochromic anemia
B.Macrocytic normochromic anemia
C.. Normocytic normochromic anemia

A

A. . Microcytic hypochromic anemia

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3
Q

MCV is 80-90 fL

A. Microcytic hypochromic anemia
B.Macrocytic normochromic anemia
C.Normocytic normochromic anemia

A

C.Normocytic normochromic anemia

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4
Q

Erythroblasts in the bone marrow that shows
abnormality; maturation

A. Non-megaloblastic anemia-
B.Macrocytic normochromic anemia
C.Normocytic normochromic anemia
D. Megaloblastic anemia

A

D. Megaloblastic anemia

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5
Q

Causes

B12 deficiency- pernicious anemia

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

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6
Q

Accelerated erythropoiesis

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

A. Non-megaloblastic anemia

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7
Q

Abnormalities of Vit. B12 or folate metabolism
A. Non-megaloblastic anemia
b. megaloblastic anemia

A

megaloblastic anemia

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8
Q

Folic acid deficiency- nutritional megaloblastic anemia

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

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9
Q

Drug induced disorders of DNA synthesis

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

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10
Q

Inherited disorders of DNA synthesis

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

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11
Q

causes

Increased membrane surface area

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

A. Non-megaloblastic anemia

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12
Q

Obscure causes (hypoplastic & aplastic anemias)

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

A. Non-megaloblastic anemia

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13
Q

Alcohol

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

A. Non-megaloblastic anemia

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14
Q

Liver disease
A. Non-megaloblastic anemia
b. megaloblastic anemia

A

A. Non-megaloblastic anemia

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15
Q

Cytotoxic drugs

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

A. Non-megaloblastic anemia

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16
Q

Laboratory Findings

**Red cells are macrocytic- MCV is greater than 96 fl. And often as high as 120-140 fl
**
A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

17
Q

Macrocytes are typically oval in shape

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

18
Q

Reticulocytes count is low and platelet counts may be moderately reduced, especially in severely anemic patients

A. Non-megaloblastic anemia
b. megaloblastic anemia

A

b. megaloblastic anemia

19
Q

Peripheral Smears:

Show normal RBC in morphology despite the drop of Hgb, Hct, and RBC count

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

C. Megaloblastic anemia/ MACROCYTIC

20
Q

Increased bone marrow activity (increased of reticulocyte count) without increased red cell of hgb breakdow

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

C. Megaloblastic anemia/ MACROCYTIC

21
Q

5 causes of megaloblastic anemia

A
  1. B12 deficiency- pernicious anemia
  2. Folic acid deficiency- nutritional megaloblastic anemia
  3. Abnormalities of Vit. B12 or folate metabolism
  4. Inherited disorders of DNA synthesis
  5. Drug induced disorders of DNA synthesis

“BI FAD”

22
Q

5 Causes OF NON MEGALOBLASTIC ANEMIA

A
  1. Accelerated erythropoiesis
  2. Increased membrane surface area
  3. Obscure causes (hypoplastic & aplastic anemias)
  4. Alcohol
  5. Liver disease
  6. Cytotoxic drugs- even some medicinal drugs are cancerous such
    as metronidazole (drug for amoebiasis

“LACO AI”

23
Q

CAUSES

Iron deficiency (IDA) AND
Other disorders of iron metabolism

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

A. Microcytic hypochromic anemia

24
Q

CAUSES

Disorder of globin synthesis as in thalassemia
AND
Disorders of porphyrin & heme synthesis as in sideroblastic
anemia

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

A. Microcytic hypochromic anemia

25
Q

Peripheral smears

Aniso and poikilocytosis

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

A. Microcytic hypochromic anemia

26
Q

Peripheral smears:

The RBC are microcytic since many are smaller than the nucleus of the lymphocyte

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

A. Microcytic hypochromic anemia

27
Q

The erythrocytes are hypochromic with increased central pallor

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

A. Microcytic hypochromic anemia

28
Q

** Elliptocytic and pencil-shaped forms are present**

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

A. Microcytic hypochromic anemia

29
Q

CAUSES

**Recent blood loss
AND
Overexpansion of plasma volume as in pregnancy
**

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

B. Normocytic normochromic anemia

30
Q

Renal disorders
Liver disorder

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

B. Normocytic normochromic anemia

31
Q

Hypoplastic bone marrow (aplastic anemia)

Infiltrated bone marrow (leukemia)

A

Normocytic

32
Q

Hypoplastic bone marrow (aplastic anemia)

Infiltrated bone marrow (leukemia)

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

B. Normocytic normochromic anemia

33
Q

Endocrine abnormality
Chronic disorders

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

B. Normocytic

34
Q

Normocytic normochromic anemia 9 causes

A

Causes:
1. Recent blood loss
2. Overexpansion of plasma volume as in pregnancy
3. Hemolytic diseases
4. Hypoplastic bone marrow (aplastic anemia)
5. Infiltrated bone marrow (leukemia)
6. Endocrine abnormality
7. Chronic disorders
8. Renal disorders
9. Liver disorder

ROH HI CLER

35
Q

LABORATORY findings of?

  1. Plasma volume and red cell volume- reduced in proportionate amount
  2. Hct is normal
  3. Platelet count is reduced
  4. Plasma fibrinogen level is reduced
  5. Neutrophilic leukocytosis is present
  6. Normocytes and normochromic cells are present

A. Microcytic hypochromic anemia
B. Normocytic normochromic anemia
C. Megaloblastic anemia/ MACROCYTIC
D.Non-megaloblastic anemia/MICROCYTIC

A

B.normocytic