Classification and assessment in psychiatry Flashcards
Two major classificatory systems (+dates)
ICD-10 (WHO, 1992)
DSM-IV (American Psychiatric Association, 1994)
Operationalised approach (to classification)
Essentially a ‘checklist’ approach to diagnosis:
- Precise clinical descriptions of disorders
- Predefined exclusion and inclusion criteria
- Details of the number/duration of symptoms required for diagnosis
3 kinds of symptoms relevant to the operationalised approach to classification
Characteristic symptoms - pertinent to the diagnosis (e.g. the symptoms of depression are found in many different disorders)
Pathognomonic symptoms - strongly favour one diagnosis over another (e.g. flashbacks in PTSD)
Discriminating symptoms - necessary for a diagnosis (e.g. thought insertion)
‘CPD’
Atheoretical approach (to classification)
Diseases are described according to the observed phenomenology; NOT based on an understanding of what might be causing the disturbances
(no theory - e.g. behaviourism, psychoanalytic - forms the basis of the classifications, only neutral observations are taken into account)
Descriptive approach
Illnesses are classified on the basis of what constitutes the illness, not what causes them.
This forms the basis of the atheoretical approach.
Hierarchical organisation
Certain disorders take precedence over others when making a diagnosis.
If a disorder closer to the top of the hierarchy can explain the observed symptoms, then a diagnosis should not be entertained from below even if the constellation of symptoms are suggestive of such a diagnosis
Stems from the ideas of Karl Jaspers.
Largely abandoned in DSM but maintained in ICD-10’s organisation of chapters.
Organic disorders - Substance use disorders - Psychosis - Affective disorders - Neurotic disorders - Personality issues
ICD-10 Multiaxial approach
1 - mental disorder (including personality disorder and mental handicap)
2 - degree of disability
3 - current psychosocial problems
DSM-IV Multiaxial approach
1 - clinical disorders
2 - personality disorders/mental retardation
3 - general medical conditions
4 - psychosocial and environmental problems
5 - global assessment of functioning
DSM-V (updates from DSM-IV)
Published 2013
Abandoned use of multiaxial diagnosis and global assessment of functioning
Autistic disorder, Asperger’s, and pervasive developmental disorder were consolidated into one disorder: Autistic spectrum disorder.
Binge eating disorder, premenstrual dysphoric disorder, and hoarding disorder gained recognition as ‘real’ disorders.
DSM-V (modifications to psychosis)
Removal of ‘bizarre’ delusions
Removal of subtypes of schizophrenia
3 core symptoms recognised: delusions, hallucinations, disorganised speech
Changes in schizoaffective criteria
DSM-V (modifications to mood disorders)
Dysthymia and chronic depression merged
Bereavement no longer an exclusion for depression
Premenstrual dysphoric disorder added as a new diagnosis
DSM-V (modifications to developmental disorders)
Autistic disorder, Asperger’s, and pervasive developmental disorder were consolidated into one disorder: Autistic spectrum disorder.
ADHD age criteria relaxed
Anton’s syndrome
aka Anton-Babinski syndrome
Occurs following damage to the occipital lobe.
Affected individuals are cortically blind but are unaware of this and deny they have a problem (anosognosia). It often presents as the patient starts falling over furniture as they can’t see. Affected individuals believe they can still see and describe their environments in detail but are wrong in their description (confabulation).
Anosognosia
lack of insight
multiple choice questionnaire used to rate the severity of depression.
Depending on the version used there are either 17 or 21 items. Each item is scored out of between 3 and 5 points. The greater the total points scored the more severe the depression is.
For the 17 item version (the most commonly used) scores range between 0 and 54. Scores over 24 indicate a severe depression.
HAMD (Hamilton depression rating scale)
10-item diagnostic questionnaire used to measure the severity of depressive episodes.
It was designed to be more sensitive to the changes brought on by antidepressants and other forms of treatment.
MADRS (Montgomery-Asberg depression rating scale)
assesses the severity of depression.
There are 20 items on the scale, each one scored out of 1-4.
ZSRDS (Zung self rated depression scale)
assesses the severity of depression
21 items, each scored 0-3.
The scale was revised in 1966.
0-13 indicates minimal depression,
14-19 mild depression,
20-28 moderate,
29-63 severe depression.
BDI (Beck depression inventory)
30 item self-report scale used to screen for depression in the elderly.
Each question has either a yes or no response, making the total score out of 30.
0-9 is deemed normal,
10-19 is mild depression,
20-30 is severe depression.
GDS (geriatric depression scale)
screening test for depression.
It uses a deck of cards with statements such as ‘I’ve lost interest in things’ which are shown to the patient. In response to each card, the patient indicates whether the card is true or false by pointing to another card.
There are 19 cards with a maximum score of 21 (two cards carry 2 points each).
It is a quick test and takes less than 5 minutes to administer. A cut off score of 7 is generally used.
The test was developed for use on busy wards to introduce a degree of privacy as other tests involve questions being read out and someone in the next cubicle hearing everything.
BASDEC (Brief Assessment Schedule Depression Cards)
This test was developed specifically to screen for depression in dementia cases. It involves a 20 min interview with a carer and 10 mins with the patient.
A total of 19 items are rated as either ‘absent’, ‘mild / intermittent’, or ‘severe’.
Cornell Scale for Depression in Dementia
11-item instrument used to assess the severity of mania in patients with a diagnosis of bipolar disorder.
YMRS (Young mania rating scale)
14 item scale designed to measure the severity of anxiety.
HAMA (Hamilton anxiety rating scale)
used to measure both the severity of OCD and the response to treatment.
Y-BOCS (Yale-Brown Obsessive compulsive scale)
a common instrument used to evaluate psychopathology in patients with schizophrenia, it has now been largely replaced by the PANSS.
It is rated by a clinician and consists of 24 items, each rated out of a 7 point scale of severity. Higher score indicate greater severity of symptoms.
Ratings for several of the variables are based on observation, the remainder are assessed via a short interview.
BPRS (Brief psychiatric rating scale)
looks at both positive and negative symptoms in schizophrenia. It takes a wide sample of information, including data from and interview, along with reports from hospital staff and family. The information gathered is based on how the patient was in the previous week.
PANSS (Positive and negative syndrome scale)
used as part of axis V of the DSM-IV. It provides a single measure of global functioning.
It enquires about psychological and occupational functioning only.
The total score is out of 100. A score of 100 is the best that can be achieved and indicates that a patient functions at the highest level possible.
GAF (Global assessment of functioning)
a scale that requires the clinician to rate the severity of the patient’s illness at the time of assessment, relative to the clinician’s past experience with patients who have the same diagnosis.
CGI (Clinical global impression)
used to quantify discontinuation symptoms associated with stopping antidepressants.
43-item rating scale - spans a broad spectrum of discontinuation symptoms and can be helpful in documenting symptoms of depressed patients in order to diagnose the likely cause of distress.
DESS (Discontinuation-Emergent Signs and Symptoms scale)
BDI (Beck depression inventory)
Self-rated or clinician-rated?
Self-rated
GHQ (General health questionnaire)
Self-rated or clinician-rated?
Self-rated
GDS (geriatric depression scale)
Self-rated or clinician-rated?
Self-rated
ZSRDS (Zung self rated depression scale)
Self-rated or clinician-rated?
Self-rated
HAD (Hospital Anxiety depression scale)
Self-rated or clinician-rated?
Self-rated
EPDS (Edinburgh postnatal major depression scale)
Self-rated or clinician-rated?
Self-rated
BPRS (Brief psychiatric rating scale)
Self-rated or clinician-rated?
Clinician-rated
MADRS (Montgomery-Asberg depression rating scale)
Self-rated or clinician-rated?
Clinician-rated
HAMD (Hamilton depression rating scale)
Self-rated or clinician-rated?
Clinician-rated
HAMA (Hamilton anxiety rating scale)
Self-rated or clinician-rated?
Clinician-rated
PANSS (Positive and negative syndrome scale)
Self-rated or clinician-rated?
Clinician-rated
CGI (Clinical global impression)
Self-rated or clinician-rated?
Clinician-rated
AIMS (Abnormal involuntary movement scale)
Self-rated or clinician-rated?
Clinician-rated
Y-BOCS (Yale-Brown Obsessive compulsive scale)
Self-rated or clinician-rated?
Clinician-rated
YMRS (Young mania rating scale)
Self-rated or clinician-rated?
Clinician-rated
GAF (Global assessment of functioning)
Self-rated or clinician-rated?
Clinician-rated
SAS (Simpson-Angus scale)
Self-rated or clinician-rated?
Clinician-rated
CAMDEX (Cambridge Mental Disorders of the Elderly Examination)
Self-rated or clinician-rated?
Clinician-rated
Cornell Scale for Depression in Dementia
Self-rated or clinician-rated?
Clinician-rated
Brief Assessment Schedule Depression Cards (BASDEC)
Self-rated or clinician-rated?
Clinician-rated
Assumed that doctor knows best. Doctor decides treatment and patient is expected to simply comply
(Model of doctor-patient relationship)
Paternalistic (aka autocratic model)
Doctor provides information and the patient is left to make the choice themselves
(Model of doctor-patient relationship)
Informative
The doctor understands the patient and helps the patient make a decision based on their circumstances. This involves shared decision making and involves the participation of the patient
(Model of doctor-patient relationship)
Interpretive
The doctor acts as a friend to the patient and attempts to steer them in a particular course of action which they see is in their best interest but ultimately the choice is left to the patient
(Model of doctor-patient relationship)
Deliberative
Models of doctor-patient relationship (4)
Paternalistic (aka Autocratic)
Informative
Interpretive
Deliberative
Glasgow Coma Scale (scores for coma/impaired consciousness)
Scores range from 3 (deep coma) to 15 (normal).
Impaired consciousness is rated as:
mild (13-15),
moderate (9-12),
severe (3-8).
GCS (E)
4 Spontaneous opening
3 Opens to verbal stimuli
2 Opens to pain
1 No response
GCS (V)
5 Orientated 4 Confused conversation 3 Inappropriate words 2 Incoherent 1 No response
GCS (M)
6 Obeys commands
5 Purposeful movement to painful stimuli
4 Withdraws in response to pain
3 Flexion in response to pain (decorticate posturing)
2 Extension in response to pain (decerebrate posturing)
1 No response
Clinical syndromes associated with substance use (8)
Acute intoxication Harmful use Dependence Withdrawal state Withdrawal delirium Psychotic disorder Amnesic syndrome Late-onset disorders
Transient disturbance in the level of consciousness, cognition, perception, affect or behaviour, or other psychophysiological functions and responses.
Acute intoxication
A pattern of substance use that is causing damage to physical or mental health.
Should not be diagnosed if dependence syndrome or substance-induced psychosis are diagnosed.
Harmful use
A cluster of behavioural, cognitive, and physiological phenomena that develop after repeated substance use and that typically include a strong desire to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to drug use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal state.
Dependence
A group of symptoms of variable clustering and severity occurring on absolute or relative withdrawal of a psychoactive substance after persistent use of that substance.
The onset and course are time-limited and are related to the type of psychoactive substance and dose being used immediately before cessation or reduction of use.
May be complicated by convulsions.
Withdrawal state
Withdrawal accompanied by confusional state
Withdrawal delirium
A cluster of psychotic phenomena that occur during or following psychoactive substance use but that are not explained on the basis of acute intoxication alone and do not form part of a withdrawal state.
Psychotic disorder (substance use syndrome)
A syndrome associated with chronic prominent impairment of recent and remote memory.
Immediate recall is usually preserved and recent memory is characteristically more disturbed than remote memory.
Disturbances of time sense and ordering of events are usually evident, as are difficulties in learning new material. Confabulation may be marked but is not invariably present. Other cognitive functions are usually relatively well preserved and amnesic defects are out of proportion to other disturbances.
Amnesic syndrome
A disorder in which alcohol- or psychoactive substance-induced changes of cognition, affect, personality, or behaviour persist beyond the period during which a direct psychoactive substance-related effect might reasonably be assumed to be operating.
Late-onset (substance use) disorders
Kraepelin Mixed States (6)
Manic Stupor Mania with poverty of thought Inhibited mania Depressive-anxious Mania Excited depression Depression with flight of ideas
Manic Stupor (mood, will, thought)
Mood - high
Will - low
Thought - low
Mania with poverty of thought (mood, will, thought)
Mood - high
Will - high
Thought - low
Inhibited mania (mood, will, thought)
Mood - high
Will - low
Thought - high
Depressive-anxious mania (mood, will, thought)
Mood - low
Will - high
Thought - high
Excited depression (mood, will, thought)
Mood - low
Will - high
Thought - low
Depression with flight of ideas (mood, will, thought)
Mood - low
Will - low
Thought - high
— refers to a deficiency in understanding, processing, or describing emotions.
- A difficulty identifying feelings and distinguishing between feelings and the bodily sensations of emotional arousal
- A difficulty describing feelings to other people
- Constricted imaginal processes, as evidenced by a scarcity of fantasies
- A stimulus-bound, externally oriented cognitive style
Alexithymia
The patient cannot read but is able to write. Understanding spoken language and conversation are intact.
This is usually due to a lesion destroying the left visual cortex, as well as the connections to the right visual cortex in the corpus callosum.
It is typically caused by an occlusion of a branch of the PCA.
Alexia without agraphia
Depressive pseudodementia
Not a diagnostic entity but a descriptive term used in old-age psychiatry.
Depression in elderly patients may present as dementia clinically.
5A’s of Alzheimer’s disease
Amnesia Aphasia Agnosia Apraxia Associated disturbances (behavioural changes, delusions, hallucinations)
Amnesia (definition)
Impaired ability to learn new information and recall previously learned information
Aphasia (definition)
Problems with language (receptive and expressive)
Agnosia (definition)
Problems with recognition, especially people
Apraxia (definition)
Inability to carry out purposeful movements despite there being no sensory or motor impairment
Distinction between dementia with lewy bodies and Parkinson’s disease dementia
Parkinson’s disease dementia is diagnosed if parkinsonian symptoms have existed for more than 12 months before dementia develops.
If motor symptoms and cognitive symptoms develop within 12 months of each other, then LWD is usually diagnosed.
Schneider’s First Rank Symptoms (6)
Not pathognomic, but are highly suggestive of a diagnosis of schizophrenia. They are not useful in prognosis.
3 Hallucinations
- 3rd person voices arguing
- Running commentary
- Thought echo
3 Delusions of thought control
- Thought withdrawal
- Thought insertion
- Thought broadcasting
3 ‘Made’ phenomena
- Made affect
- Made volition
- Made impulse
2 extras:
- Delusional perception
- Somatic passivity
Schizophrenia (ICD-10 subtypes - 9)
Paranoid Hebephrenic (aka disorganised) Catatonic Undifferentiated Post schizophrenic depression Residual Simple Other Unspecified
Paranoid schizophrenia (key features)
characterised by the preoccupation of delusions or hallucinations (typically persecutory or grandiose ones).
Hebephrenic (disorganised) schiziphrenia (characterisation)
characterised by a regression to a primitive, unorganized form of behaviour. Incongruous behaviour such as grinning is common.
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it has the worst prognosis among the subtypes of schizophrenia
Catatonic schizophrenia (characterisation)
characterised by marked disturbances in motor function such as stupor, posturing, and rigidity.
— refers to patients who lack active psychotic symptoms but still have milder symptoms such as emotional blunting, and mild loosening of association.
Residual schizophrenia
Simple schizophrenia (characterisation)
characterised by predominately negative symptoms of schizophrenia in the absence of overtly psychotic experiences.
Bouffee delirante
described by Legrain
a brief shorted lived psychosis that lasts less than 3 months.
Schizophrenia - positive symptoms (3)
Hallucinations
Delusions
Thought disorder
Schizophrenia - negative symptoms (6)
Social withdrawal Apathy Lack of energy Poverty of speech Flattening of affect Anhedonia
Schizotypal disorder (features and classification)
Features
- eccentric manners, social withdrawal, magical thinking, suspiciousness, obsessive ruminations.
- 2 year history with no schizophrenia diagnosed
In ICD-10 it is classified with schizophrenia and related disorders;
in DSM-IV it is classified with Cluster A personality disorders
De Clerambault Syndrome
Erotomania.
A DSM-IV subtype of delusional disorder where a patient falsely believes that a person with higher status is secretly in love with them.
Grandiose delusion
Belief that one has a special role, relationship, or ability.
Othello syndrome
Belief that a sexual partner is cheating on them
Persecutory delusion
Most common form of delusional disorder -
Patients are convinced that others are attempting to hurt or harm them. Can lead them to try to obtain legal recourse.
Folie a deux
Shared delusion.
A syndrome where a delusion is transmitted from one person to another.
Ekboms’ syndrome
Delusional parasitosis
The belief that the skin is infested with parasites.
Sometimes a/w cocaine use
Capgras delusion
Belief that a person close to them has been replaced by a double
Fregoli delusion
Belief that strangers are actually persons well known to the patient in disguise.
Lycanthropy
belief that one has been transformed into an animal
Cotard syndrome
belief that one does is dead or does not exist, or that a part of one’s body (e.g. organs) are not there
Delusional perception
belief that a normal percept (product of perception) has a special meaning.
Pseudocyesis
a condition whereby a woman believes herself to be pregnant when she is not. Objective signs accompany the belief such as abdominal enlargement, menstrual disturbance, apparent foetal movements, nausea, breast changes, and labour pains.
Process schizophrenia (description)
Langfeldt (1939) differentiated two groups of psychoses:
- ‘Genuine’ or ‘process’ schizophrenia - poor prognosis
- ‘Schizophreniform’ psychosis - good prognosis
(later work reclassified Langfeldt’s second category as affective disorders with psychotic features)
Approximate answers
Patient gives an incorrect response to a question, but the nature of the response suggests that they understand the question
e.g. stating that a dog has three legs
consists of 14 questions, 7 for anxiety and 7 for depression
each item is scored from 0-3
produces a score out of 21 for both anxiety and depression
severity: 0-7 normal, 8-10 borderline, 11+ case
patients should be encouraged to answer the questions quickly
Hospital Anxiety and Depression (HAD) Scale
asks patients ‘over the last 2 weeks, how often have you been bothered by any of the following problems?’
9 items which can then be scored 0-3
includes items asking about thoughts of self-harm
depression severity: 0-4 none, 5-9 mild, 10-14 moderate, 15-19 moderately severe, 20-27 severe
Patient Health Questionnaire (PHQ-9)
Duration of symptoms required for diagnosis of depression (ICD-10 and DSM-IV)
2 weeks
Grading of depression (ICD-10)
‘4-6-8 rule’
Mild depression
- 2 core symptoms, with 4 symptoms in total
Moderate depression
- 2 core symptoms, with 6 symptoms in total
Severe depression
- 2 core symptoms with 8 symptoms in total
Recurrent major depressive disorder (time criterion)
In both ICD-10 and DSM-IV this can be diagnosed if there has been at least one previous major depressive episode separated by the current episode by at least 2 months
Duration of symptoms required for diagnosis of mania (ICD-10 and DSM-IV)
7 days
or any duration if hospitalised
Duration of symptoms required for diagnosis of hypomania
4 days
Precipitants of drug-induced mania (4)
Levodopa
Corticosteroids
Anabolic-androgenic steroids
Antidepressants (tricyclic and monoamine oxidase inhibitor classes)
Rapid cycling bipolar disorder (essence)
at least four depressive, manic, hypomanic, or mixed episodes in a 12 month period
Gerald Klerman - additional Bipolar subtypes (III, IV, V, VI)
Bipolar III - Cyclothymic disorder
Bipolar IV: Hypomania or mania precipitated by antidepressant drugs
Bipolar V: Depressed patients with a family history of bipolar illness
Bipolar VI: Mania without depression (unipolar mania)
Double Depression (essence)
Episode of major depression superimposed on Dysthymia
A persistent instability of mood involving numerous periods of depression and mild elation, none of which is sufficiently severe or prolonged to justify a diagnosis of bipolar affective disorder (F31.-) or recurrent depressive disorder (F33.-)
Cyclothymia
A chronic depression of mood, lasting at least several years, which is not sufficiently severe, or in which individual episodes are not sufficiently prolonged, to justify a diagnosis of severe, moderate, or mild recurrent depressive disorder
Dysthymia
Generalised anxiety disorder - ICD-10 (symptom and duration criterion)
At least 4 symptoms should be present on most days for 6 months
Obsession - essence and criteria (4)
any thought, image, or idea that is present for a minimum of 2 weeks (ICD-10) and has the following features:
1 - acknowledged as arising from within the mind
(i.e. they are not psychotic beliefs that others have implanted the thoughts)
2 - Repetitive
3 - The patient must try to resist
4 - They are not pleasurable
Compulsion (essence)
physical or mental repetitive behaviours that are used to relieve some of the anxiety caused by the obsessions.
The person is aware that their actions are not realistically connected to what they are trying to neutralize or prevent and know they are excessive.
Abnormal grief - classification (3)
Inhibited
Chronic/Prolonged
Delayed
‘ICD’
Inhibited grief (essence)
Absence of expected grief symptoms at any stage
Delayed grief (essence)
Avoidance of painful symptoms within 2 weeks of loss
Chronic/prolonged grief (essence)
Continued significant grief related symptoms 6 months after loss
Normal grief - phases (4)
Phase I - shock and protest (few days)
- numbness, disbelief
Phase II - preoccupation (few weeks)
- yearning, anger
Phase III - disorganisation (several months)
- despair, acceptance of loss
Phase IV - resolution (1-2 years)
- gradual return to normality
PTSD - key features (3)
HYPERAROUSAL
- persistent anxiety
- irritability
- insomnia
- poor concentration
HYPERVIGILANCE
- (due to re-experiencing)
- recurrent distressing dreams
- intensive, intrusive imagery (flashbacks, vivid memories)
- difficulty recalling stressful events at will
AVOIDANCE
- of reminders/activities/places related to traumatic events
- detachment from others
- emotional numbness
- anhedonia
PTSD (duration criterion)
Onset within 6 months of trauma