Classic Labs/Findings II Flashcards

1
Q

Electrical alternans (alternating amplitude on EKG)

A

Pericardial tamponade

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2
Q

Enlarged cells with intranuclear inclusion bodies

A

“Owl eye” appearance of CMV

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3
Q

Enlarged thyroid cells with ground-glass nuclei with central clearing

A

“Orphan Annie” eyes nuclei (papillary carcinoma of the thyroid)

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4
Q

Eosinophilic cytoplasmic inclusion in liver cell

A

Mallory body (alcoholic liver disease)

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5
Q

Eosinophilic cytoplasmic inclusion in nerve cell

A

Lewy body (Parkinson disease)

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6
Q

Eosinophilic globule in liver

A

Councilman body (viral hepatitis, yellow fever), represents hepatocyte undergoing apoptosis

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7
Q

Extracellular amyloid deposition in gray matter of brain

A

Senile plaques (Alzheimer disease)

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8
Q

Giant B cells with bilobed nuclei with prominent inclusions (“owl’s eye”)

A

Reed Sternberg Cells (Hodgkin’s lymphoma)

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9
Q

Glomerulus like structure surrounding vessel in germ cells

A

Schiller Duval bodies (yolk sac tumor)

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10
Q

Hair on end (Crew-cut) appearance on x-ray

A

ß-thalassemia, sickle cell disease (marrow expansion)

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11
Q

hCG elevated

A

Choriocarcinoma, hydatiform mole (occurs with and without embry, and multiple pregnancy)

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12
Q

Heterophile antibodies

A

Infectious mononucleosis (EBV)

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13
Q

Heart nodules (granulomatous)

A

Aschoff bodies (rheumatic fever)

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14
Q

Hexagonal, double-pointed, needle-like crystals in bronchial secretions

A

Bronchial asthma (Charcot-Leyden crystals: eosinophilic granules)

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15
Q

High-level of D-dimers

A

DVT, PE, DIC

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16
Q

Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)

A

Ghon complex (1° TB: Mycobacterium bacilli)

17
Q

“Honeycomb lung” on x-ray or CT

A

Interstitial pulmonary fibrosis

18
Q

Hypercoagulability (leading to migrating DVT’s and vasculitis)

A

Trousseau syndrome (adenocarcinoma of pancreas or lung)

19
Q

Hypersegmented neutrophils

A

Megaloblastic anemia (B12 deficiency: neurlogic symptoms; folate deficiency: no neurological symptoms)

20
Q

Hypertension, hypokalemia, metabolic alkalosis

A

Conn syndrome (primary hyperaldosteronism)

21
Q

Hypochromic, microcytic anemia

A

Iron deficiency anemia, lead poisoning, thalassemia (fetal hemoglobin sometimes present)

22
Q

Increased AFP in amniotic fluid/maternal serum

A

Dating error, anencephaly, spina bifida (neural tube defects)

23
Q

Increased uric acid levels

A

Gout, Lesch-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics

24
Q

Intranuclear eosinophilic droplet-like bodies

A

Cowdry type A bodies (HSV or VZV)

25
Iron-containing nodules in alveolar septum
Ferruginous bodies (asbestosis: increased chance of mesothelioma)
26
Keratin pearls on skin biopsy
Squamous cell carcinoma
27
Large granules in phagocytes, immunodeficiency
Chediak-Higashi disease (congenital failure of phagolysosome formation)
28
"Lead pipe" appearance of colon on abdominal imaging
Ulcerative colitis (loss of haustra)
29
Linear appearance of IgG deposition on glomerular and alveolar basement membranes
Goodpasture syndrome