Classes of Enzymes

Question 1

Oxidoreductase: cofactors and common names/examples

Answer 1

• Usually with cofactors NADH/NADPH/FADH2
• Oxidase
• Hydroxlyase
• Cytochrome P450*
• Oxygenase

Question 2

Transferase: Reaction and Common Names/examples

Answer 2

AB + C A + BC

1) Aminotransferase (transaminase)
2) Kinase (Pi transferred from ATP)
3) Synthase (glycogen synthase= glycogen made)

Question 3

Hydrolase

Answer 3

• Uses H20 to break bonds
  1) Protease (see other deck to memorize these)
  2) Esterase
  3) Phosphatase
  4) Peptidase
  5) Urease

Question 4

Lyase

Answer 4

• Cleave C-C, C-S, C-N any other way than oxidation or hydrolysis, “catch all”, Reverse rxns to form bonds,Form C=C bonds by removing H2O from COH-CH
  1) Decarboxylase
  2) Aldolase
  3) Synthases

Question 5

Isomerase

Answer 5

• atoms rearranged, nothing lost or added
  1) Epimerase
  2) Racemase
  3) Mutase

Question 6

Ligase

Answer 6

• Requires ATP, forms C-C, C-S, C-O, C-N

1) Synthetase (NOT THE SAME AS SYNTHASE)