Classes of Antiarrhythmics

Question 1

Classification of Antiarrhythmics

Class I-

Answer 1

Block the sodium channels in the cell membrane during an action potential (phase 0)

Question 2

Classification of Antiarrhythmics

Class II-

Answer 2

Block beta-receptors, causing a depression of phase 4 of the action potential

Question 3

Classification of Antiarrhythmics

Class III-

Answer 3

Block potassium channels, prolonging phase 3 of the action potential

Question 4

Classification of Antiarrhythmics

Class IV-

Answer 4

Block calcium channels in the cell membrane (phase 2)

Question 5

Use of Antiarrhythmics across lifespan

Children-

Answer 5

• Monitor close, more likely to experience ADE
• Digoxin id OK for children
• Dosages should be calculated by weight and age
• Ablation procedures have been successful

Question 6

Antiarrhythmics

Adults-

Answer 6

• Used frequently in EMERGENCIES
• Monitor frequently
• Avoid use in PREG/LACT.

Question 7

Antiarrhythmics

Older adults-

Answer 7

• Frequently prescribed
• More likely to experience ADE (like children)
• Start @ low dose