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Paige: MSR Module! > Classes/MOA > Flashcards

Classes/MOA Flashcards

1
Q

MOA of acetaminophen (tylenol)

A

blocks peripheral pain impulse generation; inhibits hypothalamus heat regulation

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2
Q

MOA ibuprofen

A

inhibits COX1/COX2

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3
Q

SYNTHETIC DMARDS

A

Cellcept (semi-synthetic)

Sulfasalazine

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4
Q

Leukocyte migration inhibitor

A

colchicine

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5
Q

MOA of Rituxan

A

inhibits b-lymphocytes

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6
Q

non-purine xanthine oxidase inhibitor

A

Febuxostat (Uloric)

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7
Q

CORTICOSTEROID

A

Prednisone

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8
Q

MOA of abatacept (orencia)

A

inhibits t cells by binding to APC receptors

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9
Q

MOA of amitriptyline

A

inhibits 5HT, NE reuptake

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10
Q

IL-1 Receptor antagonist

A

Anakinra (Kinercet)

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11
Q

monoclonal antibody

A

Rituximab (Rituxan)

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12
Q

MOA of allopurinol

A

blocks uric acid production

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13
Q

MOA of hydroxychloroquine

A

T cell response suppression

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14
Q

NB-DMARDS

A

methotrexate

hydroxychloroquine

Tofacitinib (Xeljanz)

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15
Q

MOA of celecoxib (celebrex)

A

inhibits COX2

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16
Q

NB-DMARD that is a JAK inhibitor

A

Xeljanz

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17
Q

Sulfasalazine MOA

A

dec levels of IgA, IgM, RF

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18
Q

uricosuric

A

probenicid

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19
Q

Prednisone MOA

A

inhibits cytokines

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20
Q

MUSCLE RELAXANTS

A

Baclofen

Cyclobenzaprine

Dantrolene

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21
Q

MOA of probenicid

A

blocks PCT reabsorption of uric acid

22
Q

baclofen MOA

A

inhibits synaptic reflexes at SC level

23
Q

B-DMARDS

A

Etanercept (Enbrel)

Abatacept (Orencia)

Rituximab (Rituxan)

Anakinra (Kinercet)

24
Q

COX2 selective nsaid

A

celecoxib (celebrex)

25
Q

xanthine oxidase inhibitor

A

allopurinol

26
Q

NSAIDS

A

ibuprofen

celebrex

27
Q

Cellcept MOA

A

immunosuppresses both B and T cells

28
Q

T cell activation inhibitor

A

abatacept (orencia)

29
Q

MOA of tramadol (ultram)

A

mu receptor antagonist; inhibits reuptake of NE/5HT

30
Q

TNF-alpha blocker

A

Etanercept (Enbrel)

31
Q

Cyclobenzaprine MOA

A

reduces somatic motor activity

32
Q

ANTI-GOUT

A

Colchicine

Probenicid

Allopurinol

Uloric

33
Q

ANALGESICS

A

acetaminophen

tramadol

34
Q

peripherally-acting muscle relaxant

A

dantrolene

35
Q

MOA of etanercept

A

binds to TNF-alpha

36
Q

traditional nsaid

37
Q

MOA of Uloric

A

reduces uric acid production

38
Q

cholinergic agonist

A

pilocarpine

39
Q

centrally-acting muscle relaxants

A

baclofen

cyclobenzaprine

40
Q

MOA of cyclophosphamide

A

prevents cell division

41
Q

MOA of methotrexate

A

inhibits DNA production/production of cytokines

42
Q

analgesic/antipyretic

A

acetaminophen (tylenol)

43
Q

MOA of Xeljanz

A

inhibits JAK enzymes and prevents activity of immune cells

44
Q

MOA of anakinra

A

antagonist of IL-1 receptor

45
Q

anti-neoplastic, alkylating agent

A

cyclophosphamide

46
Q

synthetic opioid analgesic

A

tramadol (ultram)

47
Q

dantrolene MOA

A

inhibits release of Ca from skel muscle

48
Q

MOA of colchicine

A

inhibits leukocyte migration/phagocytes

49
Q

tricyclic antidepressant

A

amitriptyline

50
Q

pilocarpine MOA

A

acts on muscarinic receptors to stimulate salivary gland secretion

Paige: MSR Module! (5 decks)

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