Class Clicker Questions Exam 1

Question 1

Disruption of the neuronal Na and K permeability is associated with the toxic effect of chlorinated alicyclic type organochlorine.

A. True
B. False

Answer 1

B. False

Question 2

Regarding the toxicity of the various pesticides, which of the below is CORRECT?

A. Napthalene - induced oxides in the circulation can cause methemoglobenemia
B. Nicotine is a potent stimulant of the parasympathetic nervous system
C. Rotenone blocks oxidative phosphorylation
D. All of the above
E. None of the above

Answer 2

D. All of the above

Question 3

Permethrin use in cats is typically applied at 45% without toxicity.

A. True
B. False

Answer 3

B. False

Question 4

Which of the following insecticides can increase dermal absorption of DEET?

A. Carbamates
B. Nicotine
C. Pyrethoids
D. Rotenone

Answer 4

C. Pyrethroids

Question 5

With regard to toxicity which option is correct?
A. Phosphate OPs require hepatic bioactivation
B. Thiophosphate OPs require hepatic bioactivation
C. Carbamates require hepatic bioactivation
D. All of the above

Answer 5

B. Thiophosphate OPs require hepatic bioactivation

Question 6

The active ingredient of which pesticide might be used to treat the effects of Myasthenia Gravis?

A. Carbamates and organophosphates
B. Pyrethrin and Pyrethroids
C. Nicotine and neonicotinoids
D. Ivermectin

Answer 6

A. Carbamates and organophosphates

Question 7

Which of the following compounds correctly matched with its mechanism of action?

A. Pyrethrin: Monamine oxidase inhibitor
B. Ivermectin: Octopamine receptor antagonist
C. Amitraz: Alpha adrenergic receptor agonist
D. DEET: uncoupling of oxidative phosphorylation

Answer 7

C. Amitraz: Alpha adrenergic receptor agonist

Question 8

Multidrug resistance mutant dogs have an increased tolerance for ivermectin.

A. True
B. False

Answer 8

B. False

Question 9

What is the usual cause of death from organophosphate or carbamate poisoning in mammals?

A. Increased pulmonary secretions couple with respiratory failure
B. Liver toxicity and hemolysis
C. Weakness, coma and cardiovascular collapse
D. Extreme dehydration due to vomiting and diarrhea

Answer 9

A. Increased pulmonary secretions couple with respiratory failure

Question 10

Indicate the least accurate answer following acute exposure to metaldehyde.

A. Increased GABA
B. Increased monamine oxidase
C. Decreased serotonin
D. Decreased norepinephrine

Answer 10

A. Increased GABA

Question 11

What gas is directly responsible for acute toxicosis and more animal deaths in a closed space than any other gas?

A. Carbon monoxide
B. Ammonia
C. Hydrogen sulfide
D. Carbon dioxide

Answer 11

C. Hydrogen sulfide

Question 12

Which of the following gases does NOT have a toxic effect by converting to an irritating substance on contact with moist mucus membranes?

A. Ammonia
B. Nitrogen oxide
C. Carbon monoxide
D. Sulfur oxide

Answer 12

C. Carbon monoxide