Class 2 - Neoplasms of the CNS Flashcards
Brain tumors account for what percentage of all cancers?
2%
Where do brain tumors tend to metastasize?
they do not.
What percentage of malignant diseases in childhood do brain tumors make up?
20%
75% of brain tumors are of what cell origin?
glial cells
15% of brain tumors originate from what tissue?
meninges
What is the most common benign brain neoplasm?
meningiomas
Which brain neoplasm can be surgically resected without residual consequences?
meningiomas
What is the second most common intracranial tumor in adults?
meningiomas
80% of astrocytomas are…
glioblastoma multiforme
What is the most common location of glioblastoma multiforme?
cerebrum
Acoustic neuromas are characteristic of what disease?
Neurofibromatosis Type II
Ependymomas are more commonly found in ___ in children and _____ in adults.
4th ventricle in children
terminal portion of spinal cord in adults
What percentage of brain tumors are metastases from other sites?
50%
Which cancers are most likely to metastasize to the brain?
lung cancer
Where are most metastatic spinal cord tumors found? What percentage are found there?
thoracic spine (70%)
Differentiate neurofibromatosis type I vs. type II
type I sees changes in skin pigmentation and multiple tumor growth in peripheral nerves
type II grows on cranial nerve VIII and affects balance, hearing, etc
The incidence of meningiomas is __ x higher in women
10x
What are neuromas?
tumors of the cranial/spinal nerves
Which glioma has the best prognosis?
non-infiltrating astrocytomas
What is the most common and most deadly malignant brain tumor?
glioblastoma multiforme
What do glioblastomas tend to cause in the brain?
hemorrhage and necrosis
What is the prognosis for glioblastomas?
12-18 months
When is the peak incidence of glioblastoma multiforme?
65 years old
What is the survival rate of oligodendrogliomas?
5-10 years in 80% of people
