CLASP Alcohol Flashcards
How is methanol toxicity treated
With ethanol
Both metabolised by alcohol dehydrogenase
Alcohol is mainly absorbed by
The small intestine
Where is alcohol metabolised
~90% in the liver
How does alcohol cause ketoacidosis
By impairing oxidation and building up ketones
Alcohol inhibits ADH causing what?
Reduced water resorption and clearer urine
What kind of effect does acute alcohol ingestion have on the heart?
Negative inotropic effect
How much is one unit in ethanol?
10ml or 8 grams
Define hazardous drinking
Drinking that increases the risk of harmful consequences
14-35 units for women
14-50 units for men
Define harmful drinking
Drinking that causes mental of physical damage
35 for women
50 for men
Define alcohol dependence
A strong desire to drink alcohol and difficulties controlling it’s use
How many units per person (without non-drinkers) did 2017 alcohol sales total to?
24 units per week
What is the alcohol use disorders identification test (AUDIT)?
A 10 question harm screening tool from the WHO
A score above 20 means there is a possible dependence
What is the drug of choice for medically assisted detoxification?
Chlordiazepoxide
Complications of withdrawal
Seizures
Hallucinations
Derlirium tremens
Wernicke-Korsakoff Syndrome
Pharmacological treatments for relapse prevention
Acamprosate
Naltrexone
Disulfiram