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UBSPPS PHM601 Flashcards Renal-Primary Prevention > CKD MBD > Flashcards

CKD MBD Flashcards

1
Q

Goals of therapy of CKD-MBD

A

Serum calcium 8.5-10.2
Phosphorous 2.7-4.6 or 3.5-5.5
iPTH 150-600

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2
Q

Counseling point for phosphate binders

A

Take with food

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3
Q

What are the calcium based phosphate binders

A

Calcium carbonate

Calcium acetate

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4
Q

Calcium carbonate dose

A

1250mg TID with meals

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5
Q

Calcium acetate dose

A

1334mg TID with meals

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6
Q

Which calcium based phosphate binder is available over the counter?

A

Calcium carbonate

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7
Q

Calcium based phosphate binders have drugs interactions with…

A

Flurooquinolones
Levothyroxine
Iron

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8
Q

What are the non calcium based phosphate binders?

A

Sevelamer carbonate
Sevelamer HCl
Lanthanum carbonate
Aluminum hydroxide

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9
Q

What is Sevelamer carbonate’s brand name?

A

Renvela

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10
Q

What is Sevelamer HCl’s brand name?

A

Renagel

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11
Q

What is Lanthanum carbonate’s brand name?

A

Fosrenol

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12
Q

What is Aluminum hydroxide’s brand name?

A

Amphojel

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13
Q

Clinical pearl for lanthanum carbonate

A

Must be chewed

Take other medications 1 hour before or 3 hours after

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14
Q

Clinical pearl for sevelamer carbonate

A

First line

Take other medications 1 hour before or 3 hours after

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15
Q

What are the iron based phosphate binders?

A

Ferric citrate

Sucroferric oxyhydroxide

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16
Q

What is ferric citrate’s brand name?

A

Auryxia

17
Q

What is Sucroferric oxyhydroxide’s brand name?

A

Velphoro

18
Q

Sucroferric oxyhydroxide pearls

A

No affect on iron levels

Lower pill burden

19
Q

Ferric citrate pearls

A

Will increase iron levels a bit

20
Q

What are the aluminum based phosphate binders?

A

Aluminum hydroxide

21
Q

Aluminum hydroxide pearls

A

Last line

risk of aluminum toxicity

22
Q

Vitamin D2 is also known as…

A

Ergocalciferol

23
Q

Vitamin D3 is also known as…

A

Cholecalciferol

24
Q

1,25-OH D3 is also known as…

A

Calcitriol

Active form

25
Q

What is Cinacalcet’s brand name?

A

Sensipar

26
Q

Cinacalcet Dosing

A

30 mg/day QD

Titrate up to 180mg QD

27
Q

Cinacalcet AEs

A

GI
Hypocalceemia
QTc prolongation

28
Q

CKD-MBD patient with high phosphate and low calcium should get

A

Calcium phosphate based binder

29
Q

CKD-MBD patient with high phosphate and normal-high calcium should get

A

Non calcium based phosphate binder

30
Q

CKD-MBD patient with corrected phosphate and low calcium should get

A

Activated Vitamin D and analogs

31
Q

CKD-MBD patient with corrected phosphate and high calcium should get

A

Calcimimetic

32
Q

What are the calcimimetics

A

Cinacalcet and Etelacalcitide

33
Q

What is Etelacalcitide’s brand name?

A

Parasbiv

UBSPPS PHM601 Flashcards Renal-Primary Prevention (12 decks)

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