CKD drugs Flashcards
what should you give for Anaemia?
Epoietin alfa
what is the MOA for epoietin alfa
Stimulates erythropoiesis
contraindication for epoietin alfa
uncontrolled HTN
what are the adverse effects of epoietin alfa?
URTI, oedema
Hypertension, seizures, heart failure, MI, stroke
what are the adverse effects of epoietin alfa?
URTI, oedema
Hypertension, seizures, heart failure, MI, stroke
what should you give for hyperkalemia
Sodium polystyrene sulfonate,
Sodium zirconium cyclosilicate
what is the moa for Sodium polystyrene sulfonate,
Sodium zirconium cyclosilicate
Bind to the excess potassium in the bowels excreted from the body through the stool.
Capture potassium in exchange for calcium or sodium ions found in the colon
what are the adverse effects of Sodium polystyrene sulfonate,
Sodium zirconium cyclosilicate
Oedema, Hypokalaemia,
Constipation, Diarrhoea
Faecal impaction,
Nausea,
Vomiting
Low calcium and magnesium level, Retention of sodium ions
Abdominal discomfort, Bloating
what should you give for hyperphosphotaemia
Calcium carbonate,
Calcium acetate,
Sevelamer,
Lanthanum (PO)
Adverse effects of calcium carbonate
Oedema, Hypophosphatemia,
Constipation,
Abdominal discomfort, Bloating
What should you give for hyperparathyroidism
Calcitriol,
Cinacalcet
(PO, iv)
MOA of calcium carbonate
An active form of vitamin D3elevates the plasma levels of calcium stimulating intestinal calcium uptake, increasing reabsorption of calcium by the kidneys.
Adverse effects of calcium carbonate
Minor hypokalaemia, postural hypotension, tinnitus, nausea, diarrhoea, dizziness, fatigue,
Significant hypokalaemia, blood dyscrasias, dehydration, ototoxicity, electrolyte imbalance, circulatory co
