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BIOCHEMISTRY (PART 2) > Citric acid cycle > Flashcards

Citric acid cycle Flashcards

1
Q

The name Citric acid cycle is after?

A

since it’s the first product in the cycle

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2
Q

The fuel in the citric acid cycle?

A

Acetyl CoA

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3
Q

the oxidizing agent in C=O IS?

A

NAD

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4
Q

the oxidizing agent in C=C is?

A

FAD

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5
Q

At what part is FAD used as oxidizing agent?

A

Succinate - Fumarate

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6
Q

What is the enzyme used in Succinate - Fumarate?

A

Succinate dehydrogenase

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7
Q

What is the readily oxidized alcohol in the cycle?

A

Isocitrate

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8
Q

The enzyme in Citrate - Isocitrate?

A

Aconitase

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9
Q

What enzyme is used in Oxidation of Isocitrate to a-ketoglutarate?

A

Isocitrate dehydrogenase

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9
Q

What enzyme is used in Oxidation of Isocitrate to a-ketoglutarate?

A

Isocitrate dehydrogenase

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10
Q

the only ketone in the cycle?

A

a-ketoglutarate

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11
Q

What is the enzyme in the conversion of a-ketoglutarate to Succinyl CoA?

A

ketoglutarate dehydrogenase complex
(V. B and Mg2+)

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12
Q

What enzyme is in the conversion of succinyl CoA to succinate/ succinyl phosphate?

A

Succinyl CoA synthase

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13
Q

What is the bond that is broken in Succinyl CoA that produces GTP and Succinate?

A

Thioester bond

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14
Q

What is the enzyme in the conversion of Succinate to Fumarate

A

Succinate dehydrogenase

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15
Q

What is the enzyme in the conversion of Fumarate to Malate?

A

Fumarase

16
Q

Fumarase is stereospecific to _________ and catalyzes ______ to the double bond of fumarate?

A

Fumarase is stereospecific to (L isomer) and catalyzes (water) to the double bond of the Fumarate

17
Q

What is the enzyme in the conversion of L-Malate to Oxaloacetate?

A

Malate dehydrogenase

18
Q

What is the proper sequence of Krebs cycle?

A

(C)itrate
(I)socitrate
a-(k)etoglutarate
(S)uccinyl CoA
(S)uccinate
(F)umarate
L - (M)alate
(O)xaloacetate

19
Q

What are the enzyme that dehydrogen?

A

Isocitrate dehydrogenase
a-ketoglutarate dehydrogenase
Succinyl dehydrogenase
Malate dehydrogenase

20
Q

At what part of the cycle that there’s (2) GTP production?

A

In the phosphorylation of Succinyl CoA

21
Q

How many ATP is the krebs cycle in total?

A

3 NADH, 1 FADH, 2 GTP = 20 ATP

BIOCHEMISTRY (PART 2) (2 decks)

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