Cirrosis Flashcards

1
Q

Enfermedad progresiva en donde la arquitectura del hígado se remplaza por tejido fibroso y eventualmente cesa de funcionar

A

Cirrosis

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2
Q

Epidemiología

A

Bajo nivel socioeconómico
Hepatitis viral
Hepatitis autoimmune
Medicamentos
Acetaminofén (paracetamol)
Enfermedad Wilson
Criptogénicas

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3
Q

Etiología

A

Hepatitis B o C
Dragas y toxinas
Auto inmune
Cirrosis biliar primaria
Esteatosis (NASH)
Alcohol (ALD)

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4
Q

Mayo causa de cirrosis

A

Alcohol

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5
Q

Clasificación

A

Micronodular
Macronodular
Mixta

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6
Q

Etiología

A

Agente nocivo-cirrosis-carcinoma hepatocelular

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7
Q

Consumo crónico de OH ocasiona

A

Acetaldehído

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8
Q

Acetladehído activa

A

Prod. NADH
Peroxidación de lípidos

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9
Q

Prod. NADH

A

Hígado graso
Estrés oxidativo

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10
Q

Estrés oxidativo y peroxidación de lípidos

A

Lesión hepatocito

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11
Q

Físipatología explica la

A

Fibrosis hepatica

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12
Q

Incremento de presión hidrostática dentro del sistema portal y tributarias

A

Hipertensión portal

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13
Q

Presión portal

A

> 5.8 mmHg

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