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liver pathology > cirrhosis > Flashcards

cirrhosis Flashcards

1
Q

What are the physiological changes happening to liver in cirrhosis?

A

fibrosis and regenerative nodules of hepatocytes

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2
Q

what initiates fibrosis of liver in cirrhosis ?

A

transformation Growth Factor - Beta cells

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3
Q

Why is there increase in portal hypertension in cirrhosis?

A

Portal circulation vessels get thickened or blocked due to scar tissue or fibrosis, leading to portal hypertension.

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4
Q

what are the clinical features of portal hypertension?

A

ascites, splenomegaly, portal system shunt.

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5
Q

what causes portal system shunt?

A

liver cirrhosis

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6
Q

what is classic features of portal shunt?

A

esophageal varices, hemorrhoids, caput medusa

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7
Q

what is asterisks seen in?

A

liver cirrhosis

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8
Q

why does cirrhosis progress to coma?

A

increased serum ammonia

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9
Q

palmar erythema due to hyperestrinsim is seen in which diagnosis?

A

cirrhosis

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10
Q

spider angiomata is seen in which diagnosis?

A

cirrhosis

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liver pathology (11 decks)

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