Circulation Flashcards
Features of the Galen System
- Arteries and veins separate
- Veins from liver
- Ventricles interchange aterial and venous blood
The heart is a pump because
Cardiac myocyte beat spontaneously + maintains pressure
Function of atria
Receive blood from lungs/tissue
The system is ____ but commit to other systems in ____
series, parallel
Arterioles
Muscular walls, regulate local tissue flow
Microcirculation
Exchange between blood and intestinal fluid
Venules + veins
Carry blood back to heart act as a reservoir with 64% of blood
How does size and structure relate to function of vessel walls?
- Thickness = speed
- Muscle content needed to regulate flow -> largest muscle content in small vessels
- Content of elastic fibres - aorta highest
Capillary system ensures
Microcirculation to transport blood into intestinal tissue
In circulation mechanical potential is expressed by
Pressure differences
Cardiac ouput
Amount of blood that leaves the heart/ flows through vessels
Velocity
Amount of blood flowing through per unit of cross sectional area
R =
( density x diameter x velocity )/ viscosity
In laminar flow, particles in blood run _____ to each other for _____
parallel, maximum speed of propagation
Viscocity is a determinant for ______
Velocity
Erthocyte volume decreases with _____ and increases with _____
anaemia, polycythemia
Highest pressure drop in
arterioles
Large arterial pressure tells us
Pressure gradient of whole system
Pm =
(2 x Pdia + Psys) / 3
Ohm’s law in b.p. depends on
Cardiac output and peripheral resistance
Pressure gives an indication of
Mean pressure -> tissue pressure
When arterial pressure higher than systolic pressure
Kurotkoff sounds
When arterial pressure lower than diastolic pressure
Flow becomes continuous
Poiseuille’s Law
Q = K deltaPr-t / (nL) -> sum of blood flow determinants
deltaP =
Q x R (total peripheral resistance)
If you combine Poiseulle’s law + Ohm’s law you get
the reciprocal of resistance
Filtrated fluid =
Reabsorbed fluid + lympth tissue
High hydrostatic pressure / low oncotic pressure =
edema