Circulation 2 Flashcards

1
Q

Cardiac cycle describes the series of events that occur during :

A

Complete heartbeat

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2
Q

Each cycle consists of :

A

Systole (contraction) followed by Diastole (relaxation)

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3
Q

Atria & ventricles don’t contract at same time, Atrial systole :

A

Precedes Ventricular systole

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4
Q

The duration of each cycle =

A

0.8 second

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5
Q

5 Phases of cardiac cycle :

A

Atrial systole phase, Isovolumetric contraction phase, Ventricular ejection phase, Isovolumetric relaxation phase, Ventricular filling phase

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6
Q

In atrial systole phase, The volume of blood inside each ventricle at the end of the phase is called :

A

End diastolic volume

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7
Q

In atrial systole phase, The volume of blood inside each ventricle at the end of the phase is called end Diastolic volume & is about :

A

135 ml

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8
Q

In isovolumetric contraction phase the ventricles start to contract & blood return back to atria through AV valves leading to :

A

Closure of AV valves (tricuspid& bicuspid)

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9
Q

In isovolumetric contraction phase the ventricles start to contract leading to Closure of AV valves giving :

A

First heart sound

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10
Q

In ventricular ejection phase, The volume of blood remains in each ventricle at end of phase is called :

A

End systolic volume

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11
Q

In ventricular ejection phase, The volume of blood remains in each ventricle at end of phase is called end Systolic volume & is about :

A

65 ml

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12
Q

In Isovolumetric relaxation phase, the blood pressure inside ventricles decrease & blood return to ventricles through semilunar valves leading to :

A

Closure of semilunar valves (pulmonary & aortic valves)

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13
Q

In Isovolumetric relaxation phase, the blood pressure inside ventricles decrease & blood return to ventricles through semilunar valves leading to Closure of semilunar valves giving :

A

Second heart sound

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14
Q

In ventricular filling phase, enumerate the percent of blood in atria had passed into ventricles :

A

70%

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15
Q

First heart sound occurs during the involumetric contraction phase due to closure of :

A

Atrioventricular valves

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16
Q

First heart sound like :

A

Lub

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17
Q

Second heart sound like :

A

Dub

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18
Q

Second heart sound occurs during the involumetric relaxation phase due to closure of :

A

Aortic & Pulmonary valves

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19
Q

Name the abnormal heart sounds :

A

Heart Murmurs

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20
Q

Cardiac output (CO) is the :

A

Volume of blood pumped from each ventricle per minute

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21
Q

Cardiac output (CO) =

A

Heart rate x Stroke volume
~75/min x 70 ml
= ~5 liters/min

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22
Q

Sympathetic stimulation Increases cardiac output by increasing :

A

Heart rate & Contractility

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23
Q

Adrenaline & noradrenaline Increases cardiac output by increasing :

A

Heart rate & Contractility

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24
Q

Parasympathetic (vagus) stimulation Decreases cardiac output by :

A

Decreasing heart rate

25
Arterial blood pressure (ADP) is pressure exerted by circulating blood upon the :
Blood vessels walls
26
Systolic blood pressure (SBP), during systole, ABP increases by blood pumping into aorta. Average SBP is :
120 mmHg
27
Average Diastolic blood pressure (DBP) is :
80 mmHg
28
Pulse pressure normal value is :
40 mmHg
29
3 Factors which determine arterial blood pressure :
Cardiac output (CO): heart rate x stroke volume, Total peripheral resistance: arteries diameter, Blood volume
30
Cardiovascular centers present in :
Medulla
31
Name pressor area that sends impulses to heart via sympathetic fibers to increase HR & force of contraction leading to increase CO & ABP :
Cardiac simulatory center (CSC)
32
Name pressor area that increases ABP :
Vasoconstrictor area
33
Name depressor area that sends impulses to heat via parasympathetic fibers to decrease HR leading to decrease CO & ABP :
Cardiac inhibitory center (CIC)
34
Name depressor area that decreases ABP :
Vasodilator center (VDC)
35
The activity of cardiovascular centers is regulated by impulses coming from higher centers in brain & from :
Arterial baroreceptors
36
Arterial baroreceptors present in :
Aortic arch & Carotid sinus
37
Arterial baroreceptors detect changes in :
ABP
38
Arterial baroreceptors send impulses to :
Medullary cardiovascular centers
39
Renin-angiotensin system ; Name the peptide produced by liver :
Angiotensinogen
40
Angiotensinogen is converted to :
Angiotensin I by Renin
41
Name an enzyme produced by Kidneys in response to decrease ABP :
Renin
42
Angiotensin I is converted to Angiotensin II by :
Angiotensin converting enzyme (ACE)
43
Angiotensin II increases ABP by :
Vasoconstriction & Aldosterone hormone stimulation
44
Aldosterone hormone is secreted from :
Adrenal gland
45
Aldosterone increases :
Na+ & Water reabsorption by kidney
46
Vasopressin hormone ; ADH is secreted from :
Pituitary gland
47
ADH produces :
VC
48
ADH increases :
Water reabsorption by kidney
49
Hypertension is a persistent elevation of arterial blood pressure above :
140/90 mmHg
50
Essential (Primary) hypertension ; 90% of cases has no :
Clear cause
51
Secondary hypertension ; 10% of cases has :
Secondary to other diseases
52
Hypotension is a state of lowered arterial blood pressure below :
90/60 mmHg
53
Name 2 causes of Hypertension :
Hemorrhage & Fluid loss
54
it is a state of Acute Circulatory Failure resulting in Inadequate Tissue Perfusion & tissue Ischemia & Hypoxia :
Shock
55
Name a shock that is due to nervous conditions that lead to marked Decrease Sympathetic & Increase Parasympathetic :
Neurogenic shock
56
Name a shock that due is due to marked Decrease in Cardiac Output as in Heart failure :
Cardiogenic shock
57
Name a shock that is due to Reduced blood volume as in severe Hemorrhage :
Hypovolemic shock
58
Name a shock that is due to severe Allergy (hypersensitivity) leading to Histamine release which causes severe Vasodilation :
Anaphylactic shock
59
Name a shock that is due to Septicemia & Toxins release which cause severe Vasodilation :
Septic shock