Circuit Organisation

Question 1

Name the 5 ingredients of circuit function

Answer 1

Electrical activity of neurons
Synaptic connections
Intrinsic/endogenous properties
Simple building blows know of larger circuits based on different types of synaptic activity
Different postsynaptic receptors in different neurons for the same NT

Question 2

Name the 6 types of synapse activity

Answer 2

Recurrent inhibition
Recurrent excitation
Cyclic inhibition
Mutual (reciprocal) inhibition
Coupling by way of directly opposed electrical junctions
Electrical coupling via presynaptic fibres

Question 3

Endogenous bursting

Answer 3

Pacemaker like activity

Question 4

Plateau potentials

Answer 4

Persistent depolarised state

Once triggered cell can fire APs without continuous excitatory drive

Question 5

Post inhibitory rebound

Answer 5

PIR

Increased neuronal excitability following a period of inhibition

Question 6

4 reasons why synapses are important:

Answer 6

1) connect neurons to form circuits
2) act as info filter based on individual properties
3) can change in LT/ST- basis of memory and learning
4) major sites for circuit dysfunction and toxins