Circadian Rhythms Flashcards
1
Q
biological rhythms
A
- distinct patterns of change within the body activity
- they conform to cyclical time periods
- influenced by endogenous pacemakers (internal body clocks) and exogenous zeitgebers (external changes)
2
Q
circadian rhythms
A
- 24 hours long
- regulate several body processes, e.g. core body temperature and sleep/wake cycle
3
Q
hormones affected by circadian clock
A
- melatonin and cortisol
4
Q
sleep/wake cycle affected by daylight
A
- daylight is a very important exogenous zeitgeber
- the affect that it has on out sleep/wake cycle is demonstrated by people feeling sleepy at night and alert in the daytime
5
Q
Sleep/wake cycle breakdown
A
- core temperature reaches minimum at around 4:30am when we are asleep
- melatonin starts to be produced around 8/9pm, and stops around 7/8am
- deepest sleep is at 2/3am
- there is also a shorter and shallower period of sleepiness at 2/3pm
6
Q
Siffre’s cave study - aim
A
- wanted to investigate the effects of a lack of exogenous zeitgebers on our sleep/wake cycle
- he was studying ‘free-running’ circadian rhythms
7
Q
Siffre’s cave study - method
A
- Siffre spent multiple extended periods underground, in a cave
- he was deprived of expose to natural light and sound
- he did still have food and water
- he re-surfaced after two months, in mid-september of 1962
- however, he believed it to be mid-August
- a decade later he did a similar experiment, this time for 6 months in Texas
8
Q
Siffre’s cave study - findings
A
- he found that his sleep/wake cycle settled at around 25 hours, as opposed to being 24
9
Q
Wever and Aschoff (1976) - aim
A
- investigate sleep/wake cycle without any exogenous zeitgebers
10
Q
Wever and Aschoff (1976) - method
A
- group of participants stayed in a WW2 bunker for 4 weeks, without any natural light
11
Q
Wever and Aschoff (1976) - findings
A
- the sleep/wake cycle of all of the participants seem to increase to between 24 and 25 hours, bar one, whose cycle increased to 29hrs
- suggests that natural sleep/wake cycle is actually longer than 24hrs, but is reduced by exogenous zeitgebers, e.g. mealtimes, daylight hours, conditioning, clocks, etc.
12
Q
Folkard et al. (1985)
A
- study with group fo 12 people
- they lived in a cave for 3 weeks
- they were instructed to go to bed when the clock showed 23:45 and wake when it showed 7:45
- the clock was gradually sped up by the researchers as the study went on, unbeknownst to the participants
- the once 24hr day was reduced to 22hrs
- however, only one of the 12 participants was comfortable with the shorter cycle
- this suggests that the free-running rhythm can’t easily be altered by changing exogenous zeitgebers
- therefore we shouldn’t overestimate the influence of environment cues on our internal body clock
13
Q
(+) EVAL - practical application to shift work
A
- there is a greater understanding of the negative consequences which may occur as a result of disrupting circadian rhythms thanks to the studies done
- desynchronisation is the name given to this disruption
- night workers on shifts may experience reduced concentration around 6am due to chemicals being secreted in line with out sleep/wake cycle
- this could mean that accidents are much more likely to happen, according to Boivin et al. (1996)
- a correlation between shift work and poor health is suggested by research
- heart disease is 3x more likely to develop in shift workers according to Knutsson (2003)
- this may relate to the stress of adjusting to different sleep/wake patterns and lack of sleep
14
Q
(+) EVAL - practical application to drug treatment
A
- circadian rhythms co-ordinate heart rate, digestion, hormone levels and other systems
- understanding of circadian rhythms is therefore important to pharmacokinetics, the action of drugs on the body, how well they are absorbed and how well they are distributed
- through research, certain peak times have been identified where drugs are most effective
15
Q
(-) EVAL - use of case studies and small samples
A
- in all of the studies, a small sample is used, or just one participant
- the generalisability of the findings is affected by this, since the people involved may not be representative of the wider population
- as an example of this, Siffre found that his internal clock was much slower on his earlier study when he was younger compared to later on
- as for siffre’s study, the presence of artificial light may also affect results, acting as an alternative exogenous zeitgeber, as well as others