Circadian Rhythms Flashcards

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1
Q

biological rhythms

A
  • distinct patterns of change within the body activity
  • they conform to cyclical time periods
  • influenced by endogenous pacemakers (internal body clocks) and exogenous zeitgebers (external changes)
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2
Q

circadian rhythms

A
  • 24 hours long

- regulate several body processes, e.g. core body temperature and sleep/wake cycle

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3
Q

hormones affected by circadian clock

A
  • melatonin and cortisol
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4
Q

sleep/wake cycle affected by daylight

A
  • daylight is a very important exogenous zeitgeber
  • the affect that it has on out sleep/wake cycle is demonstrated by people feeling sleepy at night and alert in the daytime
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5
Q

Sleep/wake cycle breakdown

A
  • core temperature reaches minimum at around 4:30am when we are asleep
  • melatonin starts to be produced around 8/9pm, and stops around 7/8am
  • deepest sleep is at 2/3am
  • there is also a shorter and shallower period of sleepiness at 2/3pm
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6
Q

Siffre’s cave study - aim

A
  • wanted to investigate the effects of a lack of exogenous zeitgebers on our sleep/wake cycle
  • he was studying ‘free-running’ circadian rhythms
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7
Q

Siffre’s cave study - method

A
  • Siffre spent multiple extended periods underground, in a cave
  • he was deprived of expose to natural light and sound
  • he did still have food and water
  • he re-surfaced after two months, in mid-september of 1962
  • however, he believed it to be mid-August
  • a decade later he did a similar experiment, this time for 6 months in Texas
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8
Q

Siffre’s cave study - findings

A
  • he found that his sleep/wake cycle settled at around 25 hours, as opposed to being 24
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9
Q

Wever and Aschoff (1976) - aim

A
  • investigate sleep/wake cycle without any exogenous zeitgebers
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10
Q

Wever and Aschoff (1976) - method

A
  • group of participants stayed in a WW2 bunker for 4 weeks, without any natural light
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11
Q

Wever and Aschoff (1976) - findings

A
  • the sleep/wake cycle of all of the participants seem to increase to between 24 and 25 hours, bar one, whose cycle increased to 29hrs
  • suggests that natural sleep/wake cycle is actually longer than 24hrs, but is reduced by exogenous zeitgebers, e.g. mealtimes, daylight hours, conditioning, clocks, etc.
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12
Q

Folkard et al. (1985)

A
  • study with group fo 12 people
  • they lived in a cave for 3 weeks
  • they were instructed to go to bed when the clock showed 23:45 and wake when it showed 7:45
  • the clock was gradually sped up by the researchers as the study went on, unbeknownst to the participants
  • the once 24hr day was reduced to 22hrs
  • however, only one of the 12 participants was comfortable with the shorter cycle
  • this suggests that the free-running rhythm can’t easily be altered by changing exogenous zeitgebers
  • therefore we shouldn’t overestimate the influence of environment cues on our internal body clock
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13
Q

(+) EVAL - practical application to shift work

A
  • there is a greater understanding of the negative consequences which may occur as a result of disrupting circadian rhythms thanks to the studies done
  • desynchronisation is the name given to this disruption
  • night workers on shifts may experience reduced concentration around 6am due to chemicals being secreted in line with out sleep/wake cycle
  • this could mean that accidents are much more likely to happen, according to Boivin et al. (1996)
  • a correlation between shift work and poor health is suggested by research
  • heart disease is 3x more likely to develop in shift workers according to Knutsson (2003)
  • this may relate to the stress of adjusting to different sleep/wake patterns and lack of sleep
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14
Q

(+) EVAL - practical application to drug treatment

A
  • circadian rhythms co-ordinate heart rate, digestion, hormone levels and other systems
  • understanding of circadian rhythms is therefore important to pharmacokinetics, the action of drugs on the body, how well they are absorbed and how well they are distributed
  • through research, certain peak times have been identified where drugs are most effective
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15
Q

(-) EVAL - use of case studies and small samples

A
  • in all of the studies, a small sample is used, or just one participant
  • the generalisability of the findings is affected by this, since the people involved may not be representative of the wider population
  • as an example of this, Siffre found that his internal clock was much slower on his earlier study when he was younger compared to later on
  • as for siffre’s study, the presence of artificial light may also affect results, acting as an alternative exogenous zeitgeber, as well as others
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