CINV Flashcards
1
Q
- Blocks serotonin receptor peripherally in the gastrointestinal tract and centrally in the medulla
- Dolasetron, Granisetron, Ondansetron
A
Serotonin (5HT3) Receptor Antagonist
2
Q
- Unknown, thought to act by inhibiting prostaglandin synthesis in the cortex
- Dexamethasone, Methylprednisolone
A
Corticosteroid
3
Q
- Used in combination with other antiemetic drug (5HT3 blockers) for preventing acute and delayed nausea and vomiting.
- Aprepitant or Fosaprepitant
A
Neurokinin-1 Receptor Antagonist
4
Q
The following are the first line medications:
A
- Serotonin (5HT3) Receptor Antagonist
- Corticosteroid
- Neurokinin-1 Receptor Antagnost
5
Q
- Blocks dopamine receptor in the CTZ
- Stimulation of cholinergic activity in the gut
- Increasing GUT motility
- Antagonizes peripheral serotonin receptor in the intestine
Prochlorperazine, Chlorpromazine, Promethazine
A
Benzamide Analogs
6
Q
Similar and as effective as phenothiazine
A
Butyrophenone
7
Q
- Used in combination with other antiemetic
- Anterograde amnesia helps prevent anticipatory Nausea and Vomiting
- Lorazepam & Alprazolam
A
Benzodiazepines
8
Q
Inhibition of prostaglandin and blockade of adrenergic
A
Cannabinoid
9
Q
Preferred route for pain management
A
Oral route
10
Q
● Either somatic (arising from skin, bone, joint, muscle, or connective tissue) or visceral (arising from the internal organs such as large intestine or pancreas)
● Throbbing or localized
A
Nociceptive Pain
11
Q
Pain sustained by abnormal processing of sensory input by peripheral or CNS
A
Neuropathic Pain
