Churg Strauss Flashcards

1
Q

¿Que otro nombre recibe la enfermedad de Churg Strauss?

A

Granulomatosis eosinofilica con poliangeitis

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2
Q

Incidencia:

A

1 por cada 100,000 hbts
H: M 1,5:1

Edad: 50 años

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3
Q

Principal causa de muerte es:

A

De origen cardiaco: Arteritis de coronarias

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4
Q

SPOILER ENARM

Para ENARM pensar en paciente con:

A

Asma + eosinofilia periferica (>10%) + fromacion de granulomas extravasculares

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5
Q

Diagnostico:

A

Asma
Eosinofilia
Afectacion nasal o paranasal

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6
Q

¿Cual es un hallazgo paraclinico esperado?

A

Positividad de los anticuerpos antineutrofilo contra mieloperoxidasa

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7
Q

¿Cual es el metodo diagnostico definitivo?

A

Biopsia de uno de los organos afectados

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8
Q

Diagnostico inicial de Chrug Strauss:

A

Anticuerpos p-ANCA positivos

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9
Q

Diagnostico confirmatorio / definitivo de Churg Strauss:

A

Biopsia de organos afectados

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10
Q

Tratamiento incial de Churg Strauss:

A

Prednisona (6-12 semanas)

Alternativa: Prednisona + Ciclofosdamida

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11
Q

Tratamiento de mantenimiento de Churg Strauss:

A

Azatioprina de 12 a 18 meses

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12
Q

RELACIONA LOS HLA

Lupus Eritematoso Sistemico:

A

HLA-DR2 y DR3

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13
Q

RELACIONA LOS HLA

Artritis Reumatoide:

A

HLA-DR1 y DR4

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14
Q

RELACIONA LOS HLA

Enfermedad celiaca:

A

HLA-DQ2 y DQ8

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15
Q

RELACIONA LOS HLA

Espondilitis anquilosante:

A

HLA-B27

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