chronic kidney disease/end stage Flashcards

1
Q

chronic kidney dz?

A

decline in GFR over months to years

>70% due to DM and HTN

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2
Q

s/s of CKD?

A
HYPERTENSION
asymptomatic in early stages but progressive decline in gfr
cognitive decline over time
drug toxicity
hypoglycemia (dont clear insulin)
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3
Q

diag criteria of CKD

A
  • document elevation in serum crea over >3mo

- persistent proteinuria or abnormal renal imaging

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4
Q

tx of CKD

A
CONTROL BP
tx of underlying cause
tx of comorbities
refer stg 3-5
avoid nephrotoxic drugs
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5
Q

uremic syndrome?

A

uremia = build up of nitrogenous wastes (END ORGAN DAMAGE)

-common in ESRD w/ GFR<10

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6
Q

end stage renal dz?

A
  • stage 5 of CKD
  • GFR declines to 5-10mL/min/1.73m2
  • most pts dont get here bc they die earlier
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7
Q

ESRD s/s

A
  • uremia
  • general: fatigue, n/v, cognitive issues
  • decline in kidney func over time
  • HTN
  • fluid retention
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8
Q

ESRD lab results

A

BROAD WAXY CASTS
GFR<10
elevated BUN/creat

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9
Q

ESRD tx?

A

renal replacement therapy to sustain life:

  • hemodialysis
  • peritoneal dialysis
  • kidney transplant
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