Chronic Kidney Disease Flashcards
5 functions of the kidney
Fluid Balance Produces EPO Acid-Base Balance Toxin Excretion Regulates osmolarity
Creatinine
waste product of muscle metabolism
purely excreted by kidneys
longstanding measure of kidney function
Proteinuri/ Albuminuria
leaking into the urine
(urine dipstick - doesn’t quantify or take into account concentration)
Albumin/Creatine ratio
CKD Staging
Stage 1 >90
Stage 2 60-89
Stage 3a 45-59
CKD treatment
Control diabetes - HbA1C <7%
Control BP - 140/90
Natural History of Diabetic Nephropathy
Hyperfiltration
Proteinuria
Decline in eGFR
End Stage Renal Disease
Aneamia
- Reduced EPO production
- Build up of Hepcidin- reduces uptake of iron from the gut - give IV
Renal Replacement Therapy
Haemodialysis
Peritoneal Dialysis
Kidney Transplant
Conservative/ Palliative Care
Dialysis instead of transplant?
Age >65, eGFR <15