Chronic Kidney Disease

Question 1

CKD Definition

Answer 1

GFR or equal to less than 60 for THREE months with or kidney damage for 3 months without decreased GFR

Question 2

Staging of CKD

Answer 2

Stage 1: Kidney damage with normal or increased GFR (>90mL/min)
Stage 2: Mild reduction in GFR (60-89mL/min)
Stage 3: Moderate reduction in GFR (30-59mL/min)
Stage 4: Severe reduction of GFR (15-29 mL/min)
Stage 5: Kidney failure (GFR<15mL/min or dialysis)

Question 3

CrCl (female)

Answer 3

CrCl (male) x 0.85

Question 4

CrCl (male)

Answer 4

([140-age] x weight in kg)/(serum Cr x 72)

Question 5

Albuminuria Levels

Answer 5

A1 less than 30 normal-mild increase
A2 30-300 Moderately increased
A3 300 Severely increased

Question 6

Indications for dialysis?

Answer 6

Hyperkalemia
Severe metabolic acidosis
pericarditis

Question 7

Pre-transplant immunosuppression:

Protocol used:

Answer 7

24 hours before Tx:
Steroids (prednisone) 5mg/kg/
Mycophenolate Mofetil 500-1000 mg BD
1 hour before Tx: basiliximab (Simulect) 20mg iv (stat)
(To be repeated on day 4 after tx).
All recipients are started on Gancyclovir and Broad Spectrum Antibiotic Prophylaxis before surgery

Question 8

Follow up schedule for Tx patients:

Answer 8

1st month: 3 times a week
1-3months: once a week
3-6months: once every 2 weeks
6 months-2 years: once a month
2 years and over: every 2 months