Chronic Injury Flashcards
How do regeneration & fibrosis affect permanent repair?
The fibrosed area matures & contracts, the epitherlium thickens, resulting in a fully regenerated epithelium with an underlying area of scar tissue
When does a permanent scar occur?
When damage is deeper than 33% skin thickness or takes more than 3 weeks to heal
What is scar tissue comprised of?
Disorganised collagen matrix produced by myofibroblasts
What are the characteristics of a normal scar?
- Confined to edges of original wound
- Gradual fading and atrophy
- No treatment
- Best in elderly
What are the characteristics of a hypertrophic scar?
- Confined to edges of original wound
- Regresses after initial peak (often over several years)
- Treatment: Silicone patches or gels
- Worst in the young
What are the characteristics of a keloid scar?
- Extends beyond edges of wound
- Progressive
- Treatment: Intralesional steroids
- More common in darker skin
- Failure of apoptosis
What are the types of treatment for skin wound healing?
Silica gel patches, compression, hydrotherapy, steroid injections, laser, liquid nitrogen
How are muscle tears classified?
Grade 1, 2, 3 tears - grade 3 is complete tear with complete loss of function
What is the treatment for muscle tears?
Rest (less than 1 week)
What occurs during the late phase of muscle repair?
- Atrophy from injury & disuse
- Reduced length
- Reduced flexibility/elasticity
- Reduced cardio training
- Reduced whole body stability, core strength & agility
What are the symptoms of late stages of repair?
- Shortened tissue length
- Tenderness, sensitivity or pain when performing the movement
- Stiff to get moving, sore after exercise
- Weak, poorly controlled, fatigues early
How can lung tissue be damaged?
By infections, chronic inflammation & chronic lung diseases
What are the characteristics of pulmonary fibrosis (lung scarring)
- Shortness of breath
- Dry cough
- Fatigue, weakness
- Loss of appetite, weight loss
What are the treatments for damaged lung tissue?
- Breathing exercises
- Physical training for inspiratory muscles & peripheral muscles
What are the rough recovery times for:
- Muscle strain
- Ligament
- Bone
- Chondral cartilage
- Vessel
- Tendon
- Strength
- Control/skill
- Muscle strain: 3 days-6 weeks
- Ligament: 4-8 weeks
- Bone: 6-8 weeks
- Chondral cartilage: 6 weeks-never
- Vessel: Up to 3 weeks
- Tendon: 3-18 months
- Strength: 6-8 weeks
- Control/skill: 2-4 weeks