Chronic cancer pain Flashcards

1
Q

Acute pain

A

Transmitted via Aδ fibres (fast)

Examples:

  • headache
  • post operative pain
  • post injury pain
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2
Q

Chronic pain

A

Transmitted via C fibres (slow)

Examples:

  • cancer pain
  • lower back pain
  • osteoarthritic pain
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3
Q

Components of a pain assessment

A

A focused patient history

A thorough and focused physical examination and documentation of findings

Additional medical diagnostic procedures

The use of standardised pain assessment tools

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4
Q

Pain assessment tools

A

Numeric

Descriptive

Visual analogue score

Faces

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5
Q

Patients’ barriers to pain and assessment and treatment

A

Reluctance to report pain

  • might indicate serious problem
  • trying to be a ‘good’ patient
  • fear of diagnostic tests/ procedures

Reluctance to take medication

  • fear of addiction
  • worries about side effects

Language, previous experiences etc

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6
Q

HCP’s barriers to pain assessment and treatment

A

Reluctance to prescribe pain medication

  • fear of addiction
  • worries about side effects
  • concern that attention may encourage medication seeking behaviour

Inadequate knowledge and experience

Failure to routinely assess and document

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7
Q

Nociceptive pain

A

Nociceptor stimulation by noxious stimuli
- chemical, mechanical or thermal

Further subdivided into somatic and visceral

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8
Q

Neuropathic pain

A

Pathological changes in, or damage to, the CNS or PNS

Arises from neural tissue

Clinical descriptions variable

  • continuous ‘burning’ ‘aching’
  • spontaneous ‘lancinating’ ‘electric’

Associations

  • allodynia
  • hyperalgesia
  • hyperpathia
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9
Q

Somatic pain

A

Arises from bone, muscle, cutaneous and connective tissue

Localised

Typically clinically described as throbbing or stabbing

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10
Q

Visceral pain

A

Arises from internal organs

Generalised/ diffuse

Clinically, typically described as cramping or gnawing

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11
Q

Somatic pain characteristics

A

Origin: stimulation of nociceptors

Nerve function: normal

Location of injury: tissue

Description: throbbing, sharp, stabbing

Abnormal sensations: none

Responds to opioid analgesic: tends to respond

Examples: arthritis, metastatic bone pain

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12
Q

Visceral pain characteristics

A

Origin: stimulation of nociceptors

Nerve function: normal

Location of injury: abdominal, thoracic or pelvic viscera

Description: gnawing, cramping

Abnormal sensations: none

Response to opioid analgesic: tends to respond

Examples: cholecystitis, pancreatitis

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13
Q

Neuropathic pain characteristics

A

Origin: nerve damage

Nerve function: abnormal

Location of injury: central/ peripheral nervous system

Description: burning, shooting, tingling, aching

Abnormal sensations: common

Response to opioid analgesic: less response

Examples: post herpetic neuralgia, diabetic distal sensory peripheral neuropathy, phantom limb pain

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14
Q

Relative potency compared to oral morphine

A

Alfentanil x30

Buprenorphine x100

Codeine x0.1

Diamorphine x3

Fentanyl x100

Morphine sulfate

Oxycodone x1.5-2

Tramadol x0.2

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15
Q

Oral morphine use

A

Moderate to severe pain

Help breathlessness

Quick acting, works after about 30 minutes

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16
Q

Side effects of morphine

A

Constipation

Nausea

Drowsiness

Toxicity

  • myoclonic jerking
  • hallucinations
17
Q

Oral morphine sulfate pharmacology

A

Bioavailability: 35%

Peak effect: ≤60 minutes

Time to Pmax: 15-60 minutes

Plasma 1/2 life: 1.5-4.5 hours

Duration of action: 3-6 hours