Chromosome And genes Flashcards
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1 dna is approximately how long?
2m
Nucleosomes
Hiistones with dna molecules wrapped around them
…. does not transcribe any proteins and Gennes. Found very close to the ventromere and ends of the chromosome
Heterochromatin
Difference between centromere and kinetochore
Centromere is constricted reason, kinetochere is protein complex arranged on centromere
Four types of chromosomes on location of centromere in order
Metacentric
Submetacentric
Akrocentric
Telocentric
Linked genes?
Gene’s found very close together on the locus of a chromosome
How many groups of chromosomes are there depending on length and morphology
7 a. 1 to 3 b. 4 to 5 c. 6 to 12 D. 13 to 15 E. 16 to 18 F. 19 and 20 G. 21 and 22 Sex chromosomes
Look at slide 30
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Type of chromosome abnormalities
Translocation
Deletions
Duplication(practically translocation but w homologous chromosomes)
Inversion
What is CpG methylating
Methylating the cytosine of a CphosphateGuanine motif to silence genes
Chromosome size in interphase and metaphase
11-30 nm
300 to 700 nm
Types of banding
Q banding - stained with a fluorescent dye such as quinacrine
G banding - staining with Giemsa after digesting the chromosomes with trypsin
R banding - produces the reverse of G band stain
C banding - chromosomes are treated with acid and base then stained with Giemsa
Remember UGRC but with a Q