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Week 51 > Christie > Flashcards

Christie Flashcards

1
Q

Triiodothyronine (T3)

A
  • 10% of Thyroid Hormone secretion
  • Active Form
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2
Q

What is the active form of Thyroid Hormone

A

T3

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3
Q

The parafollicular or C cells of the thyroid secrete

A

Calcitonin

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4
Q

Which of the following statements about T3 and T4 is true

A

Use transport sytems to cross cell membranes

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5
Q

What reaction does thyroid peroxides catalyze

A
  • oxidation of iodide ion to I2
  • organification of I2 into thyroglobulin
  • coupling reactions
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6
Q

What inhibits thyroid peroxidase

A

propylthiouracil

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7
Q

What molecule transports the majority of thyroid hormones in the blood

A

Thyroid binding globulin

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8
Q

When you suspect hyperthyroidism in a patient, what is the first test you should order.

A

TSH

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9
Q

What is a effect of thyroid hormone

A

Increases the basal metabolic rate

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10
Q

Iodide balance in the body

A

Most of the iodide in the thyroid is stored as thyroglobulin

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11
Q

Thyroid function tests are used for:

A
  • assess overall thyroid status
  • evaluate the adequacy of levothyroxine therapy
  • monitor the treatment of:
    • hyperthyroidism
    • hypothyroidism
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12
Q

Not an indication for performing thyroid function testing?

A

Monitor the treatment of hypothyroidism

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13
Q

What does not inhibit thyroid hormone function?

A

Increased TBG levels

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14
Q

T or F: “Cold” thyroid nodules are most likely to be neoplastic than are “hot” nodules.

A

true

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15
Q

Based on your present knowledge, what causes the abnormality shown here

A

Thyroglossal duct cyst

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16
Q

2 year old child

A

Thyroxine

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17
Q

What causes the condition seen in this infant?

A

Hypothyroidism

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18
Q

Goiter

A
  • Plummers syndrome is due to autonomous nodule in a multinodular goiter
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19
Q

In this euthyroid individiual who is otherwise asymptomatic, which of the following is the most likely diagnosis for this lesion?

A

simple (diffuse) goiter

20
Q

What are autoimmune diseases?

A

Graves disease

Hashimoto’s thyroiditis

21
Q

35 year old lady

A

Graves Disease

22
Q

50 year old lady

A

Hasimotos disease

23
Q

Thyroid cancer

A

Cancers metastatic to the thyroid are common

24
Q

Which of the following neoplasms is most likely to metastasize to the thyroid gland?

A

renal cell carcinoma

25
Q

Which of the following thyroid neoplasms has the worst prognosis?

A

anaplastic carcinoma

26
Q

Which of the following thyroid carcinomas is most likely to stain for amyloid?

A

Medullary Carcinoma

27
Q

Not a feature of multiple endocrine neoplasia?

A

Same age at diagnosis as sporadic cancers

28
Q

Which cells secrete PTH.

A

Chief Cells

29
Q

What cells form bone

A

osteoblasts

30
Q

What is the abnormality shown here

A

Parathyroid adenoma

31
Q

40 year old man

A

Parathyroid adenoma

32
Q

A lady with lung cancer exhibits the signs and symptoms of hypercalcemia yet here PTH is decreased. What is the cause of her hypercalcemia

A

Hypercalcemia of malignancy due to PTHrP secretion

33
Q

What is the most common cause of hypocalcemia in a hospitlized patient?

A

Decreased serum albumin

34
Q

Net effect of Vitamin D:

A
  • Increase blood calcium and phosphorus levels
35
Q

Effect of calcitriol

A
  • Increases calcium and phosphate
36
Q

T or F: In tertiary hyperparathyroidism, a patient with secondary hyperparathyroidism develops autonomous and excessive parathyroid activity often due to development of an adenoma

A

True

37
Q

Which type of MEN would be most likely in an individual with the lesions o fthe tongue shown in this illustration?

A

MEN 2b

38
Q

What is secreted by the adrenal gland?

A
  • Cortisol
  • Aldosterone
  • Catecholamines
  • DHEA
39
Q

What is primarily responsible for production of DHEA

A

Zona reticularis

40
Q

45 year old man

A

Exogenous corticosteroids

41
Q

19 year old

A

Neisseria meningitidis

42
Q

52 year old woman

A

Autoimmune destruction of the adrenals

43
Q

45 year old man

A

increased urinary free catecholamines

44
Q

Not effect of cortisol?

A

Decreased breakdown of proteins

45
Q

Most common cause of Cushing Syndrome?

A

exogenous/latrogenic corticosteroid administration

46
Q

Responsible for most symptoms of hyperaldosteronism?

A

Hypokalemia

47
Q

T or F: The distinction between metabolic syndrome and cushing syndrome is made on the basis of the anabolic changes produced by Cushing syndrome.

A

False

Week 51 (8 decks)

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