Choudhury - Secretory Function of GI Tract: Pancreas

Question 1

Two most important things we need to know for the exam regarding the pancreas’ secretory functions:

Answer 1

Secretin and “the CCK”

Question 2

CCK stimulates secretion of what chemical?

Answer 2

Pancreatic juices

Question 3

Secretin releases?

Answer 3

Bicarbonate

Question 4

What do the Islets of Langerhans produce?

Answer 4

α (A) cells (20%) - Glucagon
β (B) cells (70%) - Insulin (amylin)
d (D) cells (5%) - Somastotatin
pp cells (5%) - Pancreatic polypeptide

Question 5

Concentration of pancreatic secretions?

Answer 5

Isotonic

Question 6

Acinar cells secrete?

Answer 6

Pancreatic “juices”

Question 7

Ductal cells secrete?

Answer 7

Bicarb

Question 8

Pancreatic secretions?

Answer 8

Pancreatic secretion is opposite to stomach. Produces 2 – 3 L of bicarbonate

Question 9

Secretin

Answer 9

Secretin generates electrical gradient that favors NaHCO3 co-transport (bicarb release)

Question 10

If you have a duodenal ulcer…most likely your secretin will be…?

Answer 10

LOW

Question 11

Signs of malabsorption and indigestion appears

if pancreatic secretions falls below 10%

Answer 11

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