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Pharmacology > CHOLINOMIMETIC AGENTS > Flashcards

CHOLINOMIMETIC AGENTS Flashcards

1
Q

Bethanechol

A

Activates bowel and bladder smooth muscle
Resistant to AChE
No nicotinic activity

Postoperative ileus
Neurogenic ileus
Urinary retention

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2
Q

Carbachol

A

Resistant to AChE

Consricts pupil and relieves IOP in open-angle glaucoma

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3
Q

Methacholine

A

Stimulates Muscuranic receptors in airway when inhaled

Challenge test for diagnosis of asthma

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4
Q

Pilocarpine

A

Contracts ciliary muscle of eye and pupillary sphincter
Resistant to AChE
Crosses BBB

potent stimiulator of sweat, tears and saliva
Open- angle and closed- angle glaucoma
Xerostomia (Sjögren syndrome)

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5
Q

Donepezil, rivastigmine, galantamine

A

⬆️ACh

Alzeheimer disease

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6
Q

Neostigmine

A

⬆️ACh

Postop and neurogenic ileus
Urinary retention
Myasthenia gravis
Reversal of NMJ blockade (postop)

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7
Q

Endrophonium

A

⬆️ACh

Uses to diagnose MG, replaced by AChR Ab

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8
Q

Physostigmine

A

⬆️ACh
Crosses BBB

Antidote for anticholinergic toxicity

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9
Q

Pyridostigmine

A

⬆️ACh
⬆️muscle strength

MG (long acting)

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Pharmacology (3 decks)

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