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Pharmacology and Therapeutics > Cholinoceptor antagonists > Flashcards

Cholinoceptor antagonists Flashcards

1
Q

Unwanted effects of muscarinic receptor antagonists

A

Hot as hell-> decreased sweating, thermoregulation
Dry as a bone-> decreased secretions
Blind as a bat-> cycloplegia (ciliary muscle paralysis)
Mad as a hatter-> CNS disturbance

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2
Q

Nicotinic receptor antagonists

A

-Otherwise known as ganglion blocking drugs

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3
Q

Hexamethonium

A

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4
Q

Trimetaphan

A

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5
Q

Effect of nicotinic receptor antagonists

A

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6
Q

Hypotension caused by nicotinic receptor antagonists

A

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7
Q

alpha-bungarotoxin

A

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8
Q

Atropine

A

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9
Q

Hyoscine

A

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10
Q

Muscarinic receptor antagonists

A

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11
Q

Influence of muscarinic receptor antagonists on physiological responses

A

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12
Q

Clinical uses of muscarinic receptor antagonists

A

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13
Q

Muscarinic receptor antagonists in anaesthetic premedication

A

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14
Q

Muscarinic receptor antagonists in motion sickness

A

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15
Q

Muscarinic receptor antagonists in Parkinson’s disease

A

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16
Q

Muscarinic receptor antagonists in asthma/obstructive airway disease

A

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17
Q

Muscarinic receptor antagonists in retina examination

A

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18
Q

Muscarinic receptor antagonists in IBS

A

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19
Q

Treatment for atropine poisoning

A

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20
Q

Botulinum toxin

A

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21
Q

Signs and symptoms of atropine poisoning

A
  • headache
  • N&V
  • dry mouth
  • dysphagia (difficulty swallowing)
  • blurred vision
  • dilated pupils
  • hot, dry skin
  • dizziness
  • drowsiness
  • confusion
  • anxiety
  • seizures
  • weak pulse
  • irregular heartbeat
22
Q

Classes of cholinoceptor

A
  • Nicotinic

- Muscarinic

23
Q

Nicotinic receptors

A

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24
Q

Muscarinic receptors

A

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25
Q

Affinity

A

-strength with which the drug binds

26
Q

Efficacy

A

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Pharmacology and Therapeutics (30 decks)

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