Cholinergic Receptors Flashcards
Radial Muscle, Iris
Sym-a1, contraction (mydriasis)++
Para- none
sphincter muscle, iris
sym-none
para-m3 and m2, contraction (miosis)+++
ciliary muscle
sym-b2, relaxation for far vision+
para-M3 and m2, contraction for near vision+++
lacrimal glands
sym-a, secretion+
para-m3 and m2, secretion+++
sinoatrial node
sym-b1>b2, increase hr++
para-m2»m3, decrease hr+++
Atria
sym-b1>b2, increase contractilily and conduction velocity++
para-m2»m3, decrease contractility++ and shortened AP duration
Atrioventricular node
Sym-b1>b2, increase in automaticity and conduction velocity++
para-m2»m3, decrease in conduction velocity and AV block+++
His-purkinje system
sym-b1>b2, increase in automaticity and conduction velocity
para-m2»m3, little effect
Ventricle
sym-b1>b2, increase in contractility, conduction velocity, automaticity, and rate or idioventricular pacemakers+++
para-m2»m3, slight decrease in contractility
coronary bv
sym-a1 and a2 is constriction, b2 is dilation++
para- none
skin and mucosa bv
sym-a1 and a1, constriction+++
para - none
skeletal muscle bv
sym-a1 is constriction and b2 is dilation++
para-none
cerebral bv
sym-a1 slight constriction
para-none
pulmonary bv
sym-a1 is constriction+ and b2 is dilation
para-none
abdominal viscera bv
sym-a1 is constriction+++ and b2 is dilation+
para-none
salivary glands bv
sym-a1 and a2, constriction+++
Renal bv
symp-a1 and a2 constriction++, b1 and b2 dilation++
para-none
Veins
sym-a1 and a2 constrict, b2 dilates
trachea and bronchi smooth muscle
sym-b2,relacation
para-m2=m3, contraction
endothelium
sym-none
para-m3, activation of no synthase
bronchial glands
symp-a1 decreased secretion, b2 increased secreation
para- m3 and m2, stimulation
stomach motility and tone
sym-a1a2b1b2, decrease (usually)+
para-m2=m3, increase+++
stomach sphincters
sym-a1,contraction (usually)+
para-m3 and m2, relaxation (usually)+
stomach secretion
sym-a2, inhibition
para-m3 and m2, stimulation++
intestine motility and tone
sym- a1a2b1b2, decrease+
para-m3 and m2, increase+++
intestine sphincters
sym-a1, contraction+
para-m3 and m2, relaxation (usually)+
intestine secretion
sym-a2, inhibition
para-m3 and m2, stimulation++
gallbladder and ducts
sym-b3, relaxation+
para-M, contraction+
renin secretion (kidney)
sym-a1 decreases, b2 increases
para-none
detrusor muscle
sym-b2, relaxation++
paraM3>m2, contraction+++
trigone and sphincter
sym-a1, contraction++
para-m3>m2, relaxation++
ureter motility and tone
sym-a1, increase
para-m,increase?
uterus
sym-a1 is pregnant contraction,b2 is pregnant ad nonpregnant relaxation
para-M, variable
male sex organs
sym-a1, ejaculation+++
para-M3, erection+++
skin pilomotor muscles
sym-a1, contraction++
para-m3,m2,none?
skin sweat glands
sym-a1, localized secretion++, generalized secretion+++
para-none
spleen capsule
sym- a1 is contraction+++, b2 is relaxation+
adrenal medulla
sym-secretion of epi and norepi
para-N, none?
skeletal muscle
sym-B2, increased contractility, glycogenolysis and k+ uptake
para-none
liver
sym- a1 and b2, glycogenolysis and gluconeogenesis+++
para-none
pancreas acini
sym-a, decreased secretion+
para-m3 and m2, secretion++
parncreas islets(Beta cells)
sym-a2 is decreased secretion,, b2 is increased secretion
para-none
fat cells
a1 b1,2,and3, lipolysis+++(thermogenesis)
para-none
salivary glands
sym-a1, k+ and water secretion+
para-m3 and m2, K+ and water secretion+++
nasopharyngeal glands
sym-none
para-m3 and m2, secretion++
pineal glands
sym-B, melatonin synthesis
para-non
posterior pituitary
sym-b1, ADH secretion
