Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology. The Cholinergic Nervous System. > Cholinergic Antagonists. > Flashcards

Cholinergic Antagonists. Flashcards

1
Q

What are the effects of cholinergic antagonists?

A

They inhibit the actions of cholinergic receptors by blocking them.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 3 classes of cholinergic antagonists?

A

Anti-muscarinic.

Ganglionic blockers.

Neuromuscular blockers.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the affect of anti-muscarinic blockers?

A

They block muscarinic receptors.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the affect of ganglionic blockers?

A

They block neuro-nicotinic receptors.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the affect of neuromuscular blockers?

A

They block muscular-nicotinic receptors.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are 2 antimuscarinic agents?

A

Atropine.

Scopalamine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the 6 modes of action of antimuscarinic agents?

A

Interaction with muscarinic receptor.

Prevention of ACH from binding.

Competitive antagonism.

Blockage of cholinergic effects so sympathetic action is dominant.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What sized dose of antimuscarinic agent is needed to create a vagolytic effect?

A

A large dose.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the effects of atropine on the cardiovascular system?

A

Tachycardia.

Increase in cardiac output.

Increase in blood pressure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the effects of atropine on the GIT?

A

Relaxation of GIT.

Decreased motility.

Decreased secretions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the effects of atropine on the urinary system?

A

Relaxation of bladder muscles.

Urinary retention.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the effects of atropine on the bronchioles?

A

Decreased secretions.

Bronchodilation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the effects of atropine on the eyes?

A

Mydriasis (pupil dilation).

Cycloplegia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why should atropine not be given to animals suffering from glaucoma?

A

As it will increase ocular pressure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the effects of atropine on the sweat glands?

A

Decreased secretion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the effects of atropine on the CNS?

A

Minimal effects.

Hallucinations and excitement with large doses.

17
Q

What is the therapeutic use of scopalamine?

A

Slight sedation.

18
Q

Are herbivores or carnivores more sensitive to atropine?

A

Carnivores.

19
Q

What animals are resistant to atropine?

A

Rabbits.

20
Q

How do we test animals for atropine poisoning?

A

Urine test.

Look for mydriasis in a cats eye.

21
Q

Pirenzipine is an antimuscarinic agent for what receptors?

A

M1 receptors.

22
Q

What is the effect of pirenzipine?

A

It reduces gastric acid secretion.

23
Q

What are the effects of telenzipine?

A

It inhibits M1 receptors and reduces gastric acid secretion.

24
Q

What is the use of tropicamide?

A

It is used on the eye.

25
Q

Gylcopyrrulate is used for what purposes?

A

As a pre-anaesthetic.

Pharmacology. The Cholinergic Nervous System. (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions