Cholinergic and Anticholinergic Meds Flashcards
1
Q
Cholinergic Medications
A
- stimulate the para sympathetic nervous system by binding to the acetylcholine receptors and activate them
- stimulate the intestines and bladder resulting in increased gastric moltility and increased urinary frequency
- stimulate pupil constriciton
2
Q
Anticholinergic
A
- antagonize the PNS by binding to the acetylcholine receptors and mediating the response
- decrease GI motility, decreased GI secretions, decreased salivation, and decreased urinary frequency
- reduces sweating, increases intraocular pressure
3
Q
Cholinergic Medications (common names)
A
- Bethanechol
- Pilocarpine
- Neostigmine
- Pyridostigmine
- Donepezil
4
Q
Cholinergic Medications (uses)
A
- bethanechol is used to treat urinary retention postoperatively or that is nonobstructive
- others are used to treat alzheimer’s disease, myasthenia gravis, glaucoma
5
Q
Cholionergic Medication (adverse effects)
A
- SLUDGE
- Salivation
- Lacrimation
- Urinary Incontinence
- Diarrhea
- Gastrointestinal cramps
- Emesis
- brady/tachycardia, hypo/hyertension, dizziness, bronchospasma, sweating
6
Q
Anticholinergic Medication (names)
A
- Atropine
- Belladonna
- Scopolamine
- Benztropine
- Ipratropium
- Oxybutynin (OAB)
- Tolterodine (incontinence)
- Glycopyrrolate
7
Q
Anticholinergic Medications (Uses)
A
Parkinson’s, drug-induced extrapyramidal reactions associated with antipsychotic meds, exercise-induced asthma, chronic bronchitis, decrease salivary secretions when needed (intubation/ procedures), irritable bowel diseases, overactive bladder, neurogenic bladder
8
Q
Anticholinergic Medications (adverse effects)
A
- low therapuetic index
- tachycardia (small doses decrease HR)
- reslessness/ irritability
- hallucinations
- delirium (elderly)
- dilated pupils/ increased IOP
- Decreased Salivation/ GI secretion
- urinary retention
- decreased sweating
- decreased bronchial secretions