Cholinergic Agonists Flashcards
Ambenonium ,donepezil, galantamine + stigmine
Indirect intermediate cholinergic drug
Muscarinic action but NOT nicotinic.
Methacholine ( CVS) + bethanechol (GIT ,UB)
Does not susceptible to cholinesterase
Carbachol + bethanechol
Acts only as muscarinic action and is Negligible to cholinesterase.
Bethanechol
Acts as both muscarinic & nicotinic action .but is negligible to cholinesterase.
Carbachol
A drug used for Megacolon , a tonic bladder is …
Bethanechol
Is used for Sjögren syndrome “cevimeline” to promote salivation.
Pilocarpine
Is a DOC for emergency lowering of Intraocular pressure. “IOP”
Pilocarpine
Atropine is administered to counteract the toxicity of ………
Pilocarpine
Used as Antidote in Atropine poisoning
Physostigmine.
Used in paralytic ileus , urinary retention & myasthenia gravis.
Neostigmine
Drugs used for Alzheimer’s disease are
AntiAchE
Tacrine” hepatotoxicity” ,donepezil,rivastigmine & galantamine
Treatment of organophosphorous compounds poisoning
1- Atropine
2- Diazepam IV
3- cholinesterase reactivators ( PAM) & (DAM)
4- decontamination.
Treatment of myasthenia gavis
Neostigmine + pyridostigmine
Used for diagnosis of myasthenia gravis
Edrophonium
Used to reverse the Neuromuscular blocking agent
Neostigmine
CI of cholinergic agonists (7 points )
1- Bronchial asthma
2- hypotension
3- hyperthyroidism
4- coronary insufficiency
5- peptic ulcer
6- obstructive urinary retention
7- urinary incontinence .
Selective M3
Bethanechol
Used as antidote for tubocurarine
Neostigmine + Edrophonium
drugs used for Glaucoma are
1- Pilocarpine
2- Carbachol
3- physostigmine
4- Echothiphate
Drugs are used in Parkinsonism
(Trihexyphenidyle & Benzotropine )
Opthalmoscope examination of retina (4 drugs)
1-Homatropine
2- Eucatropine
3- cyclopentolate
4- Tropicamide
Antiemetics , motion sickness
Scopolamine (Hyoscine)
